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JI-101 is a VEGFR2 inhibitor, a compound that targets the vascular endothelial growth factor receptor 2, which plays a crucial role in angiogenesis and tumor growth. It has potential applications in cancer research and treatment.

900573-88-8

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900573-88-8 Usage

Uses

Used in Cancer Research and Treatment:
JI-101 is used as an analyte in pharmacological activity and analytical studies, focusing on the development and optimization of assay methodologies for the quantitation of VEGFR2 inhibitors. This includes the study of JI-101 alongside other inhibitors such as sunitinib, sorafenib, and pazopanib, which are involved in the treatment of various types of cancer in human and animal models, including mice.
Used in Drug Development:
JI-101 serves as a valuable tool in the development of new drugs targeting VEGFR2, contributing to the advancement of cancer therapies and the improvement of patient outcomes. Its role in research allows for a better understanding of the mechanisms of action and potential synergistic effects with other treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 900573-88-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,0,5,7 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 900573-88:
(8*9)+(7*0)+(6*0)+(5*5)+(4*7)+(3*3)+(2*8)+(1*8)=158
158 % 10 = 8
So 900573-88-8 is a valid CAS Registry Number.

900573-88-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[1-[(2-aminopyridin-4-yl)methyl]indol-4-yl]-3-(5-bromo-2-methoxyphenyl)urea

1.2 Other means of identification

Product number -
Other names JI-101

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:900573-88-8 SDS

900573-88-8Upstream product

900573-88-8Downstream Products

900573-88-8Relevant academic research and scientific papers

1,3-DIARYL SUBSTITUTED UREAS AS MODULATORS OF KINASE ACTIVITY

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Page/Page column 50; 67, (2008/06/13)

Certain chemical entities chosen from compounds of Formula 1 and pharmaceutically acceptable salts, solvates, crystal forms, chelates, non-covalent complexes, prodrugs, and mixtures thereof, are provided herein. Pharmaceutical compositions comprising at l

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