90065-24-0Relevant academic research and scientific papers
AZACYCLIC COMPOUNDS AS INHIBITORS OF SENSORY NEURONE SPECIFIC CHANNELS
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Page 50, (2010/02/10)
Compounds of the formula (I), and pharmaceutically acceptable salts thereof, are found to be antagonists of SNS sodium channels. They are therefore useful as analgesic and neuroprotective agents wherein: X is -N- or -CH-; n is from 0 to 3.
SUBSTITUTED HETEROCYCLIC COMPOUNDS
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Page 29, (2008/06/13)
Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes.
1,3,4,6,7-11B-HEXAHYDRO-7-PHENYL-2H-PYRAZINO[2,1-A]ISOQUINOLINES METHODS OF PREPARATION, AND USES AS ANTIDEPRESSANTS
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, (2008/06/13)
1,3,4,6,7-11b-Hexahydro-7-aryl-2H-pyrazino 2,1-a!isoquinolines useful as chemical intermediates and as pharmaceuticals and methods for their preparation.
1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines
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, (2008/06/13)
1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl-isoquinolines useful as chemical intermediates and as pharmaceuticals and methods for their preparation.
cis-1,3,4,6,7,11b-Hexahydro-2-methyl-7-phenyl-2H-pyrazino[2,1-a] isoquinoline: a new atypical antidepressant.
Griffith,Gentile,Robichaud,Frankenheim
, p. 995 - 1003 (2007/10/02)
Molecular modelling studies suggested the synthesis of cis-1,3,4,6,7, 11b-hexahydro-2-methyl-7-phenyl-2H-pyrazino[2,1-a]isoquinoline (7a) as a rigid analogue of the atypical antidepressant mianserin. Acylation of 2,2-diphenylethylamine with chloroacetyl c
