90072-82-5Relevant academic research and scientific papers
Synthesis and?SAR study of?acridine, 2-methylquinoline and?2-phenylquinazoline analogues as?anti-prion agents
Cope,Mutter,Heal,Pascoe,Brown,Pratt,Chen
, p. 1124 - 1143 (2007/10/03)
Transmissible spongiform encephalopathies (TSEs) are thought to arise from aggregation of a protease resistant protein denoted PrPSc, which is a misfolded isoform of the normal cellular prion protein PrPC. Using virtual high-throughp
