900810-19-7

Upstream product

• 87-42-3 6-chloropurine 
• 683275-15-2 benzoic acid (3aS,4R,5R,6aR)-(3aS,4R,5S,6aR)-2,2-dimethyl-5-oxotetrahydro-5λ4-thieno[3,4-d][1,3]dioxol-4-yl methyl ester 
• 596103-07-0 benzoic acid (3aS,4R,6aR)-2,2-dimethyl-tetrahydro-thieno[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 87-42-3 6-chloro-7H-purine 
• 152006-17-2 2,3-O-isopropylidene-L-lyxono-1,4-lactone 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1203544-69-7 ((3aS,4R,6R,6aR)-6-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)-2,2-dimethyltetrahydrothieno[3,4-d][1,3]dioxol-4-yl)methyl benzoate 
• 1203544-68-6 6-methylamino-9-[(5'-O-benzoyl-2',3'-O-isopropylidene)-4'-thio-β-D-ribofuranosyl]purine 
• 1203544-73-3 ((2R,3S,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)tetrahydrothiophen-2-yl)methanol 
• 1203544-71-1 C₃₆H₅₀IN₅O₄SSi₂ 
• 1203544-75-5 C₂₉H₄₄IN₅O₄SSi₂ 
• 1203544-83-5 (2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-((3-iodobenzyl)-amino)-9H-purin-9-yl)tetrahydrothiophene-2-carboxamide 
• 1203544-84-6 (2S,3S,4R,5R)-N-cyclopropyl-3,4-dihydroxy-5-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)tetrahydrothiophene-2-carboxamide 
• 1203544-85-7 (2S,3S,4R,5R)-N-cyclopropylmethyl-3,4-dihydroxy-5-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)tetrahydrothiophene-2-carboxamide 
• 1203544-86-8 (2S,3S,4R,5R)-N-cyclobutyl-3,4-dihydroxy-5-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)tetrahydrothiophene-2-carboxamide 
• 2500-80-3 (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrothiophene-3,4-diol 

Relevant academic research and scientific papers

Polypharmacology of N6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide (IB-MECA) and Related A3 Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPARδ Antagonist Activity Suggests Their

A3 adenosine receptor (AR) ligands including A3 AR agonist, N6-(3-iodobenzyl)adenosine-5′-N-methyluronamide (1a, IB-MECA) were examined for adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs). In

Design and synthesis of N6-substituted-4′-thioadenosine-5′-uronamides as potent and selective human A3 adenosine receptor agonists

On the basis of a bioisosteric rationale, 4′-thionucleoside analogues of IB-MECA (N6-(3-Iodo-benzyl)-9-(5′-methylaminocarbonyl-β-d- ribofuranosyl)adenine), which is a potent and selective A3 adenosine receptor (AR) agonist, were synt

Synthesis of 4'-thiopurine nucleosides using hypervalent iodine compounds

The reaction of a silylated purine base with thiofuranoid using phenyl iodosyl bis(trifluoroacetate) gave 4'-thio purine nucleosides.

Design, synthesis, and biological activity of N6-substituted-4′-thioadenosines at the human A3 adenosine receptor

A large series of N6-substituted-4′-thioadenosines were synthesized starting from d-gulonic-γ-lactone, and structure-activity relationships were studied at the human A3 and other subtypes of adenosine receptors (ARs). 2-Chloro-substi