900812-90-0Relevant articles and documents
Design, synthesis, and biological evaluation of indole derivatives as novel nociceptin/orphanin FQ (N/OFQ) receptor antagonists
Sugimoto, Yuichi,Shimizu, Atsushi,Kato, Tetsuya,Satoh, Atsushi,Ozaki, Satoshi,Ohta, Hisashi,Okamoto, Osamu
, p. 3569 - 3573 (2007/10/03)
A novel series of 2-(1,2,4-oxadiazol-5-yl)-1H-indole derivatives as nociceptin/orphanin FQ (N/OFQ) receptor antagonists was discovered. Systematic modification of our original lead by changing the pendant functional groups, linker, heterocyclic core, and