1074-16-4

Basic information

• Product Name: 2-BROMOPHENETHYLALCOHOL
• Synonyms: 2-BROMOPHENYLETHANOL;2-BROMOPHENETHYLALCOHOL;2-(2-BROMOPHENYL)ETHANOL;Benzeneethanol, 2-bromo-;2-BROMOPHENETHYLALCOHOL 99%;2-(2-Bromophenyl)ethyl Alcohol;2-Bromophenethylalcohol,99%;2-bromophenethyl alcohol or 2-(2-bromophenyl)ethyl alcohol
• CAS NO: 1074-16-4
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.06
• Product Categories: blocks;Bromides;Alcohols;C7 to C8;Oxygen Compounds
• Mol File: 1074-16-4.mol
• Article Data: 37

Chemical Properties

• Boiling Point: 97 °C0.7 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear slightly yellow/Liquid
• Density: 1.483 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0036mmHg at 25°C
• Refractive Index: n20/D 1.577(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: DMSO, Ethyl Acetate
• PKA: 14.70±0.10(Predicted)
• CAS DataBase Reference: 2-BROMOPHENETHYLALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOPHENETHYLALCOHOL(1074-16-4)
• EPA Substance Registry System: 2-BROMOPHENETHYLALCOHOL(1074-16-4)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 1074-16-4(Hazardous Substances Data)

Usage

Chemical Properties

clear slightly yellow liquid

Uses

Different sources of media describe the Uses of 1074-16-4 differently. You can refer to the following data:
1. 2-Bromophenethyl alcohol is a brominated phenethanol derivative used as a building block in the preparation or bicyclic and tricyclic heterocycles.
2. 2-Bromophenethyl alcohol is used as an end capping reagent during the synthesis of rod-coil block copolymers and also as a test compound in the study to evaluate the potential Aedes aegypti repellent chemotype.

General Description

2-Bromophenethyl alcohol is a phenethyl alcohol derivative. It participates in the preparation of novel P-chirogenic phosphines with a sulfur-chelating arm (P*,S-hybrid ligand).

InChI:InChI=1/C8H9BrO/c9-8-4-2-1-3-7(8)5-6-10/h1-4,10H,5-6H2

Upstream product

• 60-12-8 2-phenylethanol 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 13292-87-0 dimethylsulfide borane complex 
• 18698-97-0 ortho-bromophenylacetic acid 
• 951386-58-6 1-(2-(allyloxy)ethyl)-2-bromobenzene 
• 57486-69-8 methyl 2-(2-bromophenyl)acetate 
• 6630-33-7 ortho-bromobenzaldehyde 
• 130089-19-9 1-bromo-2-(2-methoxyethenyl)benzene 
• 2178-24-7 ethyl 2-(2-bromophenyl)ethanoate 
• 19472-74-3 2-(2-bromophenyl)acetonitrile 
• 96557-30-1 2-bromophenylacetaldehyde 
• 2039-88-5 2-bromostyrene 

Downstream Products

• 91523-93-2 N-<(2-bromophenethyl)oxy>phthalimide 
• 181021-20-5 2-(2-bromophenyl)-O-(tert-butyldimethylsilyl)ethan-2-ol 
• 171734-72-8 toluene-4-sulfonic acid 2-(2-bromophenyl)ethyl ester 
• 75534-18-8 1-bromo-2-(2-chloro-ethyl)benzene 
• 4702-34-5 isochroman-1-one 
• 900812-81-9 {2-[2-(2-bromo-phenyl)-ethoxymethoxy]-ethyl}-trimethyl-silane 
• 845302-47-8 1-bromo-2-[2-(methoxymethoxy)ethyl]benzene 
• 1000014-28-7 2-(2-bromophenyl)-1-triisopropylsilyloxyethane 
• 1103533-46-5 S-2-bromophenethyl ethanethioate 
• 180160-97-8 3,4-dihydrospiro[[2]benzopyran-1,4'-piperidine] 
• 252861-21-5 2-bromophenyl 1-[2'-(2''-bromophenyl)ethyl]-4-phenylpyrrole-2-carboxylate 
• 252861-23-7 2-bromophenyl 1-[2'-(2''-bromophenyl)ethyl]-4-iodopyrrole-2-carboxylate 
• 30516-40-6 3-phenyl-2,3-dihydro-1H-inden-1-ol 
• 1961-97-3 3-phenyl-1H-indene 

Relevant articles and documents

Reaction of Diisobutylaluminum Borohydride, a Binary Hydride, with Selected Organic Compounds Containing Representative Functional Groups

The binary hydride, diisobutylaluminum borohydride [(iBu)2AlBH4], synthesized from diisobutylaluminum hydride (DIBAL) and borane dimethyl sulfide (BMS) has shown great potential in reducing a variety of organic functional groups. This unique binary hydride, (iBu)2AlBH4, is readily synthesized, versatile, and simple to use. Aldehydes, ketones, esters, and epoxides are reduced very fast to the corresponding alcohols in essentially quantitative yields. This binary hydride can reduce tertiary amides rapidly to the corresponding amines at 25 °C in an efficient manner. Furthermore, nitriles are converted into the corresponding amines in essentially quantitative yields. These reactions occur under ambient conditions and are completed in an hour or less. The reduction products are isolated through a simple acid-base extraction and without the use of column chromatography. Further investigation showed that (iBu)2AlBH4 has the potential to be a selective hydride donor as shown through a series of competitive reactions. Similarities and differences between (iBu)2AlBH4, DIBAL, and BMS are discussed.

Cascade intramolecular Prins/Friedel–Crafts cyclization for the synthesis of 4-aryltetralin-2-ols and 5-aryltetrahydro-5H-benzo[7]annulen-7-ols

The treatment of 2-(2-vinylphenyl)acetaldehydes or 3-(2-vinylphenyl)propanals with BF3·Et2O results in an intramolecular Prins reaction affording intermediary benzyl carbenium ions, which are then trapped by a variety of electron-ric

Highly diastereoselective synthesis of tetralin-fused spirooxindoles via lewis acid-catalyzed C(sp3)H bond functionalization

A highly diastereoselective synthesis of tetralin-fused spirooxindole derivatives was described. Treatment of benzylidene oxindoles with a catalytic amount of Sc(OTf)3 in refluxing hexane afforded the target compounds in good chemical yields with excellent diastereoselectivities (up to >20:1). Detailed investigation of the reaction mechanism revealed that both interconversion of the two diastereomers and their solubility difference in reaction medium were the key to achieving excellent diastereoselectivities.