90085-05-5

Usage

Uses

Used in Fragrance Industry:
Methyl 2-Hydroxycyclopentylcarboxylate is used as a fragrance ingredient for its ability to impart a pleasant scent to cosmetics, personal care products, and household items.
Used in Flavor Industry:
In the food industry, Methyl 2-Hydroxycyclopentylcarboxylate is used as a flavoring agent to add a sweet, fruity note to a variety of food and beverage products, enhancing their taste profiles.

Upstream product

• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 285-67-6 Cyclopentene oxide 
• 64-19-7 acetic acid 
• 186581-53-3 diazomethane 
• 81887-89-0 2-hydroxycyclopentyl-1-carboxylic acid 

Downstream Products

• 117959-75-8 <1α(R^*S^*),2α,2(E)>-(+/-)-2-(4,8-Dimethyl-3,7-nonadienyl)-2-(formyl)-α-<3-(phenylmethoxy)propyl>cyclopentaneacetaldehyde 
• 117959-73-6 <4aβ,7aβ(E)>-(+/-)-7a-(4,8-Dimethyl-3,7-nonadienyl)hexahydro-4-<3-(phenylmethoxy)propyl>cyclopentapyran-3(1H)-one 
• 117959-74-7 <1α(R^*S^*),2α,2(E)>-(+/-)-2-(4,8-Dimethyl-3,7-nonadienyl)-2-(hydroxymethyl)-β-<3-(phenylmethoxy)propyl>cyclopentaneethanol 
• 136788-13-1 N-<1-(2-naphthylthio)ethenyl>-N-(phenylmethyl)-1-cyclopentene-1-carboxamide 
• 136788-14-2 2-(phenylmethyl)-2-azaspiro<4.4>nonan-1-one 
• 136788-15-3 octahydro-2-(phenylmethyl)-1H-2-pyrindin-1-one 
• 59253-90-6 cyclopent-1-enecarbonyl chloride 
• 1560-11-8 cyclopent-1-enecarboxylic acid 
• 94297-79-7 21a2-(phenylmethyl)-2-azaspiro<4.4>nonane 
• 175-94-0 2-azaspiro<4.4>nonane 
• 80969-64-8 <1R,2R>-1-<<2-(benzoylthio)cyclopentyl>carbonyl>-L-proline 1,1-dimethylethyl ester 
• 81024-72-8 <1R,2S>-1-<<2-(benzoylthio)cyclopentyl>carbonyl>-L-proline 1,1-dimethylethyl ester 
• 80969-61-5 <1S,2R>-1-<<2-(benzoylthio)cyclopentyl>carbonyl>-L-proline 1,1-dimethylethyl ester 
• 81024-76-2 <1S,2S>-1-<<2-(benzoylthio)cyclopentyl>carbonyl>-L-proline 1,1-dimethylethyl ester 

Relevant academic research and scientific papers

MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS

A polymer for resist use is obtainable from a monomer having formula (1) wherein R1 is H, CH3 or CF3, R2 and R3 are a monovalent hydrocarbon group, R4 to R9 are hydrogen or a monovalent hydrocarbon group, R10 is a monovalent hydrocarbon group or fluorinat

Pyrrolopyrimidine compounds containing substituted cyclopentyl group

The invention relates to the field of pharmaceutical chemistry, provides pyrrolopyrimidine compounds containing a substituted cyclopentyl group, and concretely relates to compounds represented by formula A, and stereoisomers and pharmaceutically-acceptable salts thereof. The invention also relates to methods for preparing the pyrrolopyrimidine compounds containing a substituted cyclopentyl group, represented by formula A, a medicinal composition of the compounds, and a use of the compounds in treatment of Janus kinase mediated diseases.

Developing a Biocascade Process: Concurrent Ketone Reduction-Nitrile Hydrolysis of 2-Oxocycloalkanecarbonitriles

A stereoselective bioreduction of 2-oxocycloalkanecarbonitriles was concurrently coupled to a whole cell-catalyzed nitrile hydrolysis in one-pot. The first step, mediated by ketoreductases, involved a dynamic reductive kinetic resolution, which led to 2-hydroxycycloalkanenitriles in very high enantio- and diastereomeric ratios. Then, the simultaneous exposure to nitrile hydratase and amidase from whole cells of Rhodococcus rhodochrous provided the corresponding 2-hydroxycycloalkanecarboxylic acids with excellent overall yield and optical purity for the all-enzymatic cascade.

E-Selective Horner-Wadsworth-Emmons reaction of 2-OBO-cyclopentanone for the synthesis of rac-N-Cbz-Gly-Ψ[(E)-CF=C]-Pro-OH dipeptide isostere

The Horner-Wadsworth-Emmons reactions of ethyl 2-fluoro-2- diethylphosphonoacetate with 2-(4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl) cyclopentanone (2-OBO-cyclopentanone) using n-butyllithium furnished the corresponding tetra-substituted fluoroolefin in an E-selective manner (E:Z = 95:5). A facile synthesis of rac-N-Cbz-Gly-Ψ[(E)-CF=C]-Pro-OH as a dipeptide isostere was achieved based on the E-selective Horner-Wadsworth-Emmons reaction.

Non-Cp titanium alkoxide-based homolytic ring-opening of epoxides by an intramolecular hydrogen abstraction in β-titanoxy radical intermediates

A low-valent titanium species derived in situ from Ti(O-i-Pr)4, Me3SiCl and Mg powder in tetrahydrofuran reacted with epoxides to selectively provide less hindered alcohols via a homolytic ring-opening of epoxides, in which the intermediate β-titanoxy radical intramolecularly abstracted a hydrogen atom from an alkoxy moiety in the titanium complexes.

Enantioselective hydrogenation of β-keto esters catalyzed by P-chiral bis(dialkylphosphino)ethanes-Ru(II)

Asymmetric hydrogenation of keto esters using a BisP*-RuBr2 catalyst is reported. High enantioselectivities up to 98% were achieved in the hydrogenation of β-keto esters.

Stereo- and chemoselective transfer hydrogenation of carbonyl groups with RuCl2(PPh3)3 and BINAP-Ru as catalysts and et3NH+H2PO2-·1,5H 2O as a hydrogen donor

Using Et3NH+H2PO2-.1.5 H2O as a hydrogen donor, the RuCl2(Ph3P)3, RuCl2(PPh3)3 / C and BINAP-Ru proved highly active catalysts for transfer hydrogenation of ketones under milder conditions than other hydrogen donors. 2-Methyl-, 2-chloro-, 2-(ethoxycarbonyl)cyclohexanones and -cyclopentanones were reduced to the less stable axial alcohols in excellent diastereoisomeric excess (de: 90-100%), and the carbonyl group of α,β-unsaturated ketones was selectively reduced, in contrast with other hydrogen donors the C=C bond was reduced. Copyright

Enantioselective [2,3]-wittig rearrangement via a chiral boron ester enolate

The first enantioselective [2,3]-Wittig rearrangement of α-(allyloxy)- acetates is described which involves a chiral boron enolate with a chiral bis-suifonamide ligand to afford the α-hydroxy-β-alkyl-γ,δ-unsaturated esters in a high enantioselectivity (>9

Asymmetric hydrogenation of beta- or gamma-ketoesters and beta- or gamma-ketoamides

β- or γ-Ketoesters and β- or γ-ketoamides are asymmetrically reduced with a Ru(II)-BINAP derived catalyst at about 40° C. and about 50N/mm2 of hydrogen in the presence of a strong acid.

PHOTOCYCLIZATION OF ENAMIDES. 38 REDUCTIVE PHOTOCYCLIZATION OF α-(METHYLTHIO)- AND α-(ARYLTHIO)ENAMIDES

Reductive photocyclization of α-(methylthio)enamide (2) gave exclusively six-membered lactams (3) and (4) while the same reaction of α-(arylthio)enamides (6) and (12) was found to afford five-membered lactams (7) and (13) as major products.A novel total s