90086-41-2 Usage
Uses
Used in Pharmaceutical Research:
Benzenemethanamine, 4-iodo-.alpha.-methylis utilized as a research chemical in the development of new medications, particularly those targeting the central nervous system. Its psychoactive properties and effects on neurotransmitter release make it a valuable compound for studying the mechanisms of action and potential therapeutic applications in various neurological and psychiatric disorders.
Used in Forensic Toxicology:
Benzenemethanamine, 4-iodo-.alpha.-methylis also employed in forensic toxicology for the identification and analysis of substances in biological samples, such as blood or urine. Its unique chemical structure and psychoactive effects make it a target for detection in cases involving substance abuse or intoxication.
Used in Controlled Substances Regulation:
Due to its potential for abuse and addiction, Benzenemethanamine, 4-iodo-.alpha.-methylis subject to strict control and regulation in many countries. It is used as a reference substance in the development and enforcement of drug control policies and legislation, ensuring the safety and well-being of the public.
Check Digit Verification of cas no
The CAS Registry Mumber 90086-41-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,8 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 90086-41:
(7*9)+(6*0)+(5*0)+(4*8)+(3*6)+(2*4)+(1*1)=122
122 % 10 = 2
So 90086-41-2 is a valid CAS Registry Number.
90086-41-2Relevant academic research and scientific papers
Rh(III)-catalyzed synthesis of isoquinolines using the N-Cl bond of N-chloroimines as an internal oxidant
Chu, Benfa,Fang, Lili,Guo, Shan,Qi, Bing,Shi, Pengfei,Wang, Qi,Zhu, Jin
supporting information, (2020/03/10)
The Rh(III)-catalyzed coupling of N-chloroimines with alkynes for the efficient synthesis of isoquinolines is reported. This represents the first use of the N-Cl bond of N-chloroimines as an internal oxidant for construction of the isoquinoline skeleton. The synthesis features atom and step economy, a green solvent (EtOH), mild reaction conditions, and a broad substrate scope.
Rh(III)-Catalyzed Coupling of N-Chloroimines with α-Diazo-α-phosphonoacetates for the Synthesis of 2 H-Isoindoles
Qi, Bing,Li, Lei,Wang, Qi,Zhang, Wenjing,Fang, Lili,Zhu, Jin
supporting information, p. 6860 - 6863 (2019/09/12)
We report herein the first use of N-chloroimines as effective synthons for directed C-H functionalization. Rh(III)-catalyzed coupling of N-chloroimines with α-diazo-α-phosphonoacetates allows for efficient dechlorinative/dephosphonative access to 2H-isoindoles. Further deesterification under Ni(II) catalysis enables the complete elimination of reactivity-assisting groups and full exposure of reactivity of C3 and N2 ring atoms for attaching structurally distinct appendages.
