900874-91-1Relevant academic research and scientific papers
Highly selective phosphatidylinositol 4-kinase IIIβ inhibitors and structural insight into their mode of action
Mejdrová, Ivana,Chalupská, Dominika,K?gler, Martin,?ála, Michal,Pla?ková, Pavla,Baumlová, Adriana,H?ebabecky, Hubert,Procházková, Eli?ka,Dejmek, Milan,Guillon, Rémi,Strunin, Dmytro,Weber, Jan,Lee, Gary,Birkus, Gabriel,Mertlíková-Kaiserová, Helena,Boura, Evzen,Nencka, Radim
, p. 3767 - 3793 (2015)
Phosphatidylinositol 4-kinase IIIβ is a cellular lipid kinase pivotal to pathogenesis of various RNA viruses. These viruses hijack the enzyme in order to modify the structure of intracellular membranes and use them for the construction of functional repli
