90109-65-2

Basic information

• Product Name: 3-BROMO-4-ETHOXY-5-METHOXY-BENZALDEHYDE
• Synonyms: 3-bromo-4-ethoxy-5-methoxybenzaldehyde(SALTDATA: FREE)
• CAS NO: 90109-65-2
• Molecular Formula: C₁₀H₁₁BrO₃
• Molecular Weight: 259.11
• Mol File: 90109-65-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 327.6°Cat760mmHg
• Flash Point: 151.9°C
• Appearance: /
• Density: 1.425g/cm³
• Vapor Pressure: 0.0002mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: 3-BROMO-4-ETHOXY-5-METHOXY-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-ETHOXY-5-METHOXY-BENZALDEHYDE(90109-65-2)
• EPA Substance Registry System: 3-BROMO-4-ETHOXY-5-METHOXY-BENZALDEHYDE(90109-65-2)

Safety Data

• Hazardous Substances Data: 90109-65-2(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-ethoxy-5-methoxy-benzaldehyde is a chemical compound with a molecular formula C10H11BrO3. It is a yellowish solid and is often used in the synthesis of pharmaceuticals and agrochemicals, as well as in organic chemistry research. 3-BROMO-4-ETHOXY-5-METHOXY-BENZALDEHYDE is known for its aromatic properties and is commonly used as a building block in the production of various organic compounds. It is important to handle 3-Bromo-4-ethoxy-5-methoxy-benzaldehyde with care, as it is considered to be harmful if inhaled, swallowed, or absorbed through the skin, and it can cause severe irritation to the respiratory system and skin.

InChI:InChI=1/C10H11BrO3/c1-3-14-10-8(11)4-7(6-12)5-9(10)13-2/h4-6H,3H2,1-2H3

Upstream product

• 121-33-5 vanillin 
• 74-96-4 ethyl bromide 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 75-03-6 ethyl iodide 

Downstream Products

• 90245-05-9 [1-(3-Bromo-4-ethoxy-5-methoxy-phenyl)-meth-(E)-ylidene]-cyclohexyl-amine 
• 1269592-05-3 C₁₄H₁₇BrO₄ 
• 90132-49-3 2-(4-Ethoxy-3-ethylsulfanyl-5-methoxy-phenyl)-ethylamine 
• 90132-37-9 2-(4-Ethoxy-3-methoxy-5-methylsulfanyl-phenyl)-ethylamine 
• 90132-45-9 2-[2-(4-Ethoxy-3-ethylsulfanyl-5-methoxy-phenyl)-ethyl]-isoindole-1,3-dione 
• 90132-29-9 2-Ethoxy-1-ethylsulfanyl-3-methoxy-5-((E)-2-nitro-vinyl)-benzene 
• 90132-26-6 2-Ethoxy-1-methoxy-3-methylsulfanyl-5-((E)-2-nitro-vinyl)-benzene 
• 90132-18-6 4-Ethoxy-3-ethylsulfanyl-5-methoxy-benzaldehyde 
• 952017-26-4 2-Ethoxy-1-ethylsulfanyl-5-(2-iodo-ethyl)-3-methoxy-benzene 
• 952017-21-9 2-Ethoxy-1-ethylsulfanyl-3-methoxy-5-vinyl-benzene 
• 90132-14-2 4-Ethoxy-3-methoxy-5-methylsulfanyl-benzaldehyde 

Relevant articles and documents

Asymmetrical 2,6-bis(benzylidene)cyclohexanones: Synthesis, cytotoxic activity and QSAR study

In order to develop novel anti-cancer agents, a series of asymmetrical 2,6-bis (benzylidene)cyclohexanone derivatives containing nitrobenzylidene moiety were synthesized and their cytotoxic activity were determined in vitro against MDA-MB 231, MCF-7 and SK-N-MC cell lines using MTT assay. Among the tested compounds, the highest activity against MDA-MB 231 cells was achieved by 2-(3-bromo-5-methoxy-4-propoxybenzylidene)-6-(2-nitrobenzylidene)cyclohexanone (compound 5d). Whereas, compound 5j (the 3-nitro analog of compound 5d) was the most potent compound against MCF-7 and SK-N-MC cell lines. The results indicated that the cytotoxic activity profile against different tumor cells can be optimized by desired 4-alkoxy-3-bromo-5-methoxybenzylidene scaffold.

Sulfur Analogues of Psychotomimetic Agents. 3. Ethyl Homologues of Mescaline and Their Monothio Analogues

All possible monothio analogues of the mono-, di-, and triethoxy homologues of mescaline have been synthesized and pharmacologically evaluated in man.Modifications at the ring position para to the ethylamine chain, either with a sulfur atom, a longer alkyl chain, or both, lead to compounds of high central nervous system activity.The 4-n-propoxy and 4-n-butoxy homologues and their corresponding 4-thio analogues were also synthesized and pharmacologically evaluated.The propyl homologues retain high potency, but a butyl group (either with or without a sulfur atom) leads to a decrease in activity.The m-ethyl or m-thio analogues retain some central action but the diethoxy and especially the triethoxy homologues are relatively inactive as psychotomimetic drugs.