901120-79-4

Upstream product

• 216686-77-0 3-methyl-1-(2-methylpropyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 259862-18-5 6-bromo-3-methyl-1-(2-methylpropyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 372162-74-8 5-Bromo-3-methyl-1-(2-methylpropyl)-6-[2-(trifluoromethyl)benzoyl]-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 372162-71-5 5-bromo-6-[hydroxy-[2-(trifluoromethyl)phenyl]methyl]-3-methyl-1-(2-methylpropyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 901120-17-0 5-ethylsulfanyl-1-isobutyl-3-methyl-6-(2-trifluoromethyl-benzoyl)-1H-thieno[2,3-d]pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Potent blockers of the monocarboxylate transporter MCT1: Novel immunomodulatory compounds

A novel series of potent blockers of the monocarboxylate transporter, MCT1, is disclosed. From very potent but lipophilic lead compounds, systematic changes to all parts of the molecule, targeting reduction in log D, afforded compounds with significantly