90124-40-6Relevant academic research and scientific papers
Synthesis and evaluation of 3″- and 4″-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000
Raju, Ravinder,Castillo, Bernard F.,Richardson, Stewart K.,Thakur, Meena,Severins, Ryan,Kronenberg, Mitchell,Howell, Amy R.
supporting information; experimental part, p. 4122 - 4125 (2010/04/29)
Four 3″- and 4″-deoxy and -fluorogalactosyl ceramides were synthesized, and their ability to stimulate iNKT cells, based on levels of IL-2 production, was assessed in three NKT cell receptor hybridomas. In two of the hybridomas, 1.2 and 2H4, all of the analogs were immunostimulatory, while in the 1.4 hybridoma only the 4″-fluoro analog led to the production of significant levels of IL-2.
Modified α-D-Glcρ-(1-2)-α-D-Glcρ-(1-3)-α-D-Glcρ-analogues
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, (2008/06/13)
Disclosed is the trisaccharide α-D-Glcp-(1-2)-α-D-Glcp-(1-3)-α-D-Glcp and compounds related thereto as well as pharmaceutical compositions thereof.
Modified kojibiosides analogues
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, (2008/06/13)
Disclosed are novel analogues of kojibiose and pharmaceutical compositions comprising such analogues.
Synthesis of double-chain bis-sulfone neoglycolipids of the 2''-, 3''-, 4''-, and 6''-deoxyglobotrioses
Zhiyuan, Zhang,Magnusson, Goeran
, p. 79 - 102 (2007/10/02)
2-(Trimethylsilyl)ethyl (Me3SiCH2CH2) 2,3,6-tri-O-benzoyl-4-O-(2,3-di-O-benzoyl-6-O-p-methoxybenzyl-β-D-galactopyranosyl-β-D-glucopyranoside was glycosylated with different 2-, 3-, 4-, or 6-"deoxy-D-galactose" derivatives to give the corresponding deoxytr
Preparation and calculated conformations of the 2'-, 3'-, 4'-, and 6'-deoxy, 3'-O-methyl, 4'-epi, and 4'- and 6'-deoxy-fluoro derivatives of methyl 4-O-alpha-D-galactopyranosyl-beta-D-galactopyranoside (methyl beta-D-galabioside).
Kihlberg,Frejd,Jansson,Kitzing,Magnusson
, p. 171 - 190 (2007/10/02)
The glycosyl chlorides of the 3-O-methyl (6) and 4-deoxy-4-fluoro (8) O-benzylated derivatives of D-galactopyranose and 2,3,4,6-tetra-O-benzyl-D-glucopyranose were condensed with methyl 2,3,6-tri-O-benzoyl-beta-D-galactopyranoside to give, after deprotect
On the Possibility of Direct O-1β -> -6 Acyl Migration in 1-O-Acyl-β-D-glucose Derivatives
Yoshimoto, Kimihiro,Tsuda, Yoshisuke
, p. 4335 - 4340 (2007/10/02)
In order to clarify whether or not direct O-1β -> -6 acyl migration in O-acyl-D-glucose derivatives really occurs, 3-O-methyl-1-O-myristoyl-β-D-glucopyranose and 3-deoxy-1-O-myristoyl-β-D-glucopyranose were synthesized and their acyl migration was examine
