90124-36-0

Upstream product

• 40773-64-6 methyl 4,6-O-benzylidene-3-deoxy-ribo-hexopyranoside 
• 100-39-0 benzyl bromide 
• 26922-85-0 Methyl 3-deoxy-α-D-ribo-hexopyranoside 
• 181267-59-4 Dithiocarbonic acid O-((2R,3R,4S,5R,6S)-3,5-bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-4-yl) ester S-methyl ester 
• 35303-86-7 (2R,3S,4S,5R,6S)-3,5-Bis-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-4-ol 
• 100-44-7 benzyl chloride 
• 115888-69-2 methyl 3-deoxy-D-glucoside 

Downstream Products

• 116235-08-6 methyl 2,3,6-tri-O-benzyl-4-O-(2,4,6-tri-O-benzyl-3-deoxy-β-D-ribo-hexopyranosyl)-β-D-glucopyranoside 
• 116234-98-1 methyl 2,3,6-tri-O-benzyl-4-O-(2,4,6-tri-O-benzyl-3-deoxy-α-D-ribo-hexopyranosyl)-β-D-glucopyranoside 
• 90124-41-7 2,4,6-tri-O-benzyl-3-deoxy-1-O-myristoyl-β-D-glucopyranose 
• 181489-41-8 (1S,2R,4S,5R)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181263-21-8 (1R,2S,4S,5R)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-85-7 (1R,2R,4R,5R)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-81-3 (1S,2R,4R,5R)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-80-2 (1R,2S,4R,5R)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-87-9 (1R,2R,4S,5S)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-83-5 (1S,2R,4S,5S)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-82-4 (1R,2S,4S,5S)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-88-0 (1S,2S,4S,5S)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-77-7 (1R,2R,4R,5S)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 
• 181488-73-3 (1S,2R,4R,5S)-7-(tert-Butyl-diphenyl-silanyloxy)-4,5-dimethyl-1-((2R,4aR,7R,8aR,9aS,10aS)-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-heptane-1,2-diol 

Relevant academic research and scientific papers

A process for preparing 3 - deoxy phenyl C - aminoglycoside SGLT2 inhibitor preparation method and intermediate (by machine translation)

The invention belongs to the field of medical technology, in particular to a 3 - deoxy phenyl C - aminoglycoside SGLT2 inhibitor can be industrialized preparation method, and the method relates to a key intermediate and its preparation method. The method relates to compounds 10 alkyl lithium reagent processing, with compound 9 reaction to obtain the addition product; in the acid-catalyzed reaction with methanol to obtain compound 11; compound 11 obtained compound 12, to obtain the target compound, the method has suitable for large-scale industrial characteristics. (by machine translation)

Convergent synthesis of trans-fused oxane ring systems based on NiII/CrII-mediated cross-coupling reactions

A general method for the convergent assembly of polyether structures has been developed based on a NiII/CrII-mediated cross-coupling reaction of alkenyl iodides with aldehydes. The present method allowed coupling to oxane rings via a

Complete relative stereochemistry of maitotoxin

By addressing the relative stereochemistry of the four acyclic portions via organic synthesis, the complete relative stereochemistry of maitotoxin (MTX) has been established as 1B. The relative stereochemistry of the C.1-C.15 portion was elucidated via a two-phase approach: (1) the synthesis of the eight diastereomers possible for model C, representing the C.1-C.11 portion, and the eight diastereomers possible for model D, representing the C.11-C.15 portion, and the comparison of their proton and carbon NMR characteristics with those of MTX, concluding that 9 and 35 represent the relative stereochemistry of the corresponding portions of MTX; (2) the synthesis of the two remote diastereomers 51 and 52, and comparison of their proton and carbon NMR characteristics with those of MTX, concluding that 51 represents the relative stereochemistry of the C.1-C.15 portion of MTX. The relative stereochemistry of the C.35-C.39, C.63-C.68, and C.134-C.142 acyclic portions was established via (1) the synthesis of the 8, 8, and 16 diastereomers possible for models E, F, and G, respectively, and (2) the comparison of their proton and carbon NMR characteristics with those of MTX, concluding that 81, 117, and 187, respectively, represent the relative stereochemistry of the corresponding portions of MTX. Some biogenetic considerations have been given to speculate on the absolute configuration of MTX. The vicinal proton coupling constants observed for models 51, 81, 117, and 187 were used to elucidate their preferred solution conformation. Assembling the preferred solution conformations found for the four acyclic portions allows one to suggest that the approximate global conformation of MTX is represented by the shape of a hook, with the C.35-C.39 portion being its curvature. MTX appears to be conformationally relatively rigid, except for conformational flexibility around the C.7-C.9 and C.12-C.14 portions. On the basis of the experimental results gained in the current work, coupled with those in the AAL-toxin/fumonisin area, it has been pointed out that the structural properties of 51, 81, 117, 187 and their diastereomers are inherent to the specific stereochemical arrangement of the small substituents on the carbon backbone and are independent from the rest of the molecule. Thus, it has been suggested that each of these diastereomers has the capacity to install a unique structural characteristic through a specific stereochemical arrangement of substituents on the carbon backbone, and that fatty acids and related classes of compounds may be able to carry specific information and serve as functional materials in addition to structural materials.

The substrate specificity of the enzyme amyloglucosidase (AMG). Part I. Deoxy derivatives.

The eight possible monodeoxy derivatives of methyl beta-maltoside and two bisdeoxy derivatives have been synthesized. The unprotected glycosides have all been investigated by NMR (1H and 13C) spectroscopy in order to confirm their structures and to obtain

On the Possibility of Direct O-1β -> -6 Acyl Migration in 1-O-Acyl-β-D-glucose Derivatives

In order to clarify whether or not direct O-1β -> -6 acyl migration in O-acyl-D-glucose derivatives really occurs, 3-O-methyl-1-O-myristoyl-β-D-glucopyranose and 3-deoxy-1-O-myristoyl-β-D-glucopyranose were synthesized and their acyl migration was examine