90124-69-9Relevant academic research and scientific papers
(S)-5-Benzyl- and 5-benzylidene-imidazo-4-one derivatives synthesized and studied for an understanding of their thermal reactivity
Pepino,Pelez,Faillace,Ceballos,Moyano,Argüello
, p. 60092 - 60101 (2015/02/19)
Flash vacuum as well as static pyrolysis were used to gain insight into the mechanisms of decomposition of the title compounds. They were synthesized by the use of microwave techniques that allowed better yields than the established methods. Since the benzyl compounds always open a radical channel in the thermal processes, consequently lowering the yields of other important intramolecular processes, we also started the pyrolysis with benzylidene derivatives. Detection and quantification of products accompanied by kinetic analyses were carried out for both types of compounds. The activation energies as well as the entropy contributions have been determined. Moreover, DFT calculations provided support for and corroborating of the proposed thermal pathways.
Methods for the treatment of neuroleptic and related disorders using sertindole derivatives
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, (2008/06/13)
The invention relates to methods of administering pharmaceutical compositions and dosage forms comprising the sertindole derivatives nor-sertindole, 5-oxo-sertindole, dehydro-sertindole, and dehydro-nor-sertindol. The methods of the invention are directed
PHENYL INDOLE COMPOUNDS
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, (2008/06/13)
The present invention relates to phenylindole compounds of formula I: STR1 related to atypical neuroleptic sertindole.
Furan derivatives useful for the treatment of gastro-intestinal disorders
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, (2008/06/13)
A furan derivative and a pharmaceutically acceptable salt thereof having gastrointestinal enterokinetic activity which is expected to be used in a broad spectrum of diseases associated with gastrointestinal dyskinesia.
