901265-18-7

Upstream product

• 901265-22-3 (8αR)-8α-isopropyl-6-methylene-dihydro-oxazolo[4,3-c]-[1,4]oxazine-3,5,8-trione 
• 193292-38-5 (2Z,4E)-8-[(tert-butyldimethylsilyl)oxy]-3-[[(tert-butyldiphenylsilyl)oxy]methyl]-5-methyl-2,4-octadiene 
• 427897-76-5 [(1S,2S,5S)-2-[3-(tert-butyldimethylsilanyloxy)propyl]-4-(tert-butyldiphenylsilanyloxymethyl)-2,5-dimethylcyclohex-3-enyl]-(10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-azatricyclo[5.2.1.0^1,5]dec-4-yl)-methanone 
• 912542-25-7 phenyl-carbamic acid 2-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,5-dimethyl-7-oxa-bicyclo[4.1.0]hept-3-en-1-ylmethyl ester 
• 912542-26-8 (5R,6S,9R,10S)-6-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-10-hydroxy-6,9-dimethyl-1,3-dioxa-spiro[4.5]dec-7-en-2-one 
• 912542-44-0 6-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-6,9-dimethyl-1,3-dioxa-spiro[4.5]dec-7-en-2-one 
• 912542-42-8 [2-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-2,5-dimethyl-7-oxa-bicyclo[4.1.0]hept-3-en-1-yl]-methanol 
• 912542-24-6 [6-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-3,6-dimethyl-cyclohexa-1,4-dienyl]-methanol 
• 912542-41-7 6-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-3,6-dimethyl-cyclohexa-1,4-dienecarbaldehyde 
• 912542-45-1 2-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-1-hydroxymethyl-2,5-dimethyl-cyclohex-3-enol 
• 901266-80-6 2-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-1-hydroxymethyl-2,5-dimethyl-cyclohex-3-enol 

Downstream Products

• 912542-29-1 (1R,2S,5S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-1-hydroxy-2-(3-hydroxy-propyl)-2,5-dimethyl-cyclohex-3-enecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Studies on the synthesis of quartromicins A3 and D3: Synthesis of the vertical and horizontal bis-spirotetronate fragments

Syntheses of the vertical (3) and horizontal (4) bis-spirotetronate units of quartromicins A3 and D3 are described, along with an efficient synthesis of α-hydroxy aldehyde exo-8b, a precursor to the exo-spirotetronate fragments 19 an

Synthesis of precursors of the agalacto (exo) fragment of the quartromicins via an auxiliary-controlled exo-selective Diels-Alder reaction

A direct synthesis of the α-hydroxyaldehyde exo-5, a precursor of the exo-spirotetronate subunit of the quartromicins, was achieved through an exo-selective Lewis acid-catalyzed Diels-Alder reaction of dienophile 12a and diene 1.

Diastereoselective synthesis of the endo- and exo-spirotetronate subunits of the quartromicins. The first enantioselective Diels-Alder reaction of an acyclic (Z)-1,3-diene.

[reaction: see text]. Diastereoselective syntheses of the endo- and exo-spirotetronates 1 and 2, corresponding to the galacto and agalacto fragments of quartromicins A3 and D3, are described. The key step of these syntheses are highly enantio- and diastereoselective Lewis acid catalyzed Diels-Alder reactions of the 1,1,3,4-tetrasubstituted diene 3.

Studies on the synthesis of the quartromicins: Partial stereochemical assignment of quartromicins A3 and D3 and diastereoselective synthesis of the endo- and exo-spirotetronate subunits

A partial stereochemical assignment of quartromicins A3 and D3 is presented, along with diastereoselective syntheses of the endo- and exo-spirotetronates 1 and 2, corresponding to the galacto and agalacto fragments of the proposed quartromicin stereostructure. The key steps of these syntheses are highly enantio- and diastereoselective Lewis acid catalyzed Diels-Alder reactions of 1,1,3,4-tetrasubstituted diene 24.