427897-76-5

Upstream product

• 94594-91-9 acrylcamphorsultam 
• 193292-38-5 (2Z,4E)-8-[(tert-butyldimethylsilyl)oxy]-3-[[(tert-butyldiphenylsilyl)oxy]methyl]-5-methyl-2,4-octadiene 
• 5390-04-5 pent-1-yn-5-ol 
• 193292-62-5 (E)-7-[(tert-butyldimethylsilyl)oxy]-1-[(tert-butyldiphenylsilyl)oxy]-4-methyl-3-hepten-2-one 
• 193292-63-6 7-[(tert-butyldimethylsilyl)oxy]-1-[(tert-butyldiphenylsilyl)oxy]-3-heptyn-2-one 
• 158897-35-9 (E)-tert-butyl((5-iodo-4-methylpent-4-en-1-yl)oxy)dimethylsilane 
• 104846-46-0 (4E)-5-iodo-4-methylpent-4-en-1-ol 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 61362-77-4 5-[tert-butyldimethylsilyloxy]pent-1-yne 

Downstream Products

• 427897-77-6 (1S,2S,5S)-2-[3-(tert-butyldimethylsilanyloxy)propyl]-4-(tert-butyldiphenylsilanyloxymethyl)-2,5-dimethyl-3-cyclohexene-1-carboxaldehyde 
• 427897-82-3 methyl (1S,2S,5S)-1-acetoxy-2-(3-acetoxypropyl)-4-(tert-butyldiphenylsilanyloxymethyl)-2,5-dimethyl-3-cyclohexene-1-carboxylate 
• 901265-18-7 (1R,2S,5S)-2-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-(tert-butyl-diphenyl-silanyloxymethyl)-1-hydroxy-2,5-dimethyl-cyclohex-3-enecarbaldehyde 
• 427897-79-8 (1S,2S,5S)-2-[3-(tert-butyldimethylsilanyloxy)propyl]-4-(tert-butyldiphenylsilanyloxymethyl)-1-hydroxy-2,5-dimethyl-3-cyclohexene-1-carboxaldehyde 

Relevant academic research and scientific papers

Studies on the synthesis of the quartromicins: Partial stereochemical assignment of quartromicins A3 and D3 and diastereoselective synthesis of the endo- and exo-spirotetronate subunits

A partial stereochemical assignment of quartromicins A3 and D3 is presented, along with diastereoselective syntheses of the endo- and exo-spirotetronates 1 and 2, corresponding to the galacto and agalacto fragments of the proposed quartromicin stereostructure. The key steps of these syntheses are highly enantio- and diastereoselective Lewis acid catalyzed Diels-Alder reactions of 1,1,3,4-tetrasubstituted diene 24.

Diastereoselective synthesis of the endo- and exo-spirotetronate subunits of the quartromicins. The first enantioselective Diels-Alder reaction of an acyclic (Z)-1,3-diene.

[reaction: see text]. Diastereoselective syntheses of the endo- and exo-spirotetronates 1 and 2, corresponding to the galacto and agalacto fragments of quartromicins A3 and D3, are described. The key step of these syntheses are highly enantio- and diastereoselective Lewis acid catalyzed Diels-Alder reactions of the 1,1,3,4-tetrasubstituted diene 3.