901355-55-3Relevant academic research and scientific papers
A new type of oxidation-reduction condensation by the combined use of phenyl diphenylphosphinite and oxidant
Mukaiyama, Teruaki,Kuroda, Kiichi,Maruyama, Yuji
scheme or table, p. 63 - 82 (2010/04/23)
A new type of oxidation-reduction condensation of alcohols with sulfur, nitrogen, and oxygen nucleophiles by the combined use of phenyl diphenylphosphinite (PhOPPh2) and oxidants such as azides or diethyl azodicarboxylate (DEAD) are described. In these reactions, chiral secondary and tertiary alcohols are converted into the corresponding chiral sulfides, azides, esters and ethers under mild and neutral conditions with almost complete inversion of stereochemical configuration.
