90141-21-2

Upstream product

• 141-43-5 ethanolamine 
• 99-06-9 3-Carboxyphenol 
• 19438-10-9 methyl 3-hydroxybenzoate 
• 15788-99-5 N-(2-hydroxyethyl)-3-hydroxybenzamide 

Downstream Products

• 1451377-37-9 C₂₀H₁₇NO₅ 
• 1445406-64-3 3-(4,5-dihydrooxazol-2-yl)phenyl (5-fluoropentyl)carbamate 
• 1445406-84-7 [¹⁸F]-3-(4,5-dihydrooxazol-2-yl)phenyl (5-fluoropentyl)carbamate 
• 1416734-98-9 C₁₅⁽¹¹⁾CH₂₂N₂O₃ 
• 1416734-97-8 C₁₄⁽¹¹⁾CH₁₈N₂O₃ 
• 1416734-96-7 C₁₅⁽¹¹⁾CH₂₀N₂O₃ 
• 1445406-69-8 C₁₆H₁₂N₂O₆ 
• 1416734-88-7 C₁₆H₂₁N₃O₃ 
• 1416734-86-5 C₁₆H₂₂N₂O₃ 
• 1188498-86-3 C₁₆H₂₀N₂O₃ 
• 1072880-32-0 3-(4,5-dihydrooxazol-2-yl)phenyl cyclopentylcarbamate 
• 1072880-31-9 3-(4,5-dihydrooxazol-2-yl)phenyl propylcarbamate 

Relevant academic research and scientific papers

Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields

Fatty acid amide hydrolase (FAAH) and monoglyceride lipase (MGL) are the main enzymes responsible for the hydrolysis of endogenous cannabinoids N-arachidonoylethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. Phenyl alkylcarbamates are FA

HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS

Fatty acid amide hydrolase inhibitors of the Formula (I) are provided, wherein R is a heterocyclic or heterocyclic carbonyl moiety and R' is a group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted

Three isomeric forms of hydroxyphenyl-2-oxazoline: 2-(2-hydroxyphenyl)-2- oxazoline, 2-(3-hydroxyphenyl)-2-oxazoline and 2-(4-hydroxyphenyl)-2-oxazoline

Crystal structures are reported for three isomeric compounds, namely 2-(2-hydroxyphenyl)-2-oxazoline, (I), 2-(3-hydroxyphenyl)-2-oxazoline, (II), and 2-(4-hydroxyphenyl)-2-oxazoline, (III), all C9H9NO 2 [systematic names: 2-(4,5-dihydro-1,3-oxazol-2-yl)phenol, (I), 3-(4,5-dihydro-1,3-oxazol-2-yl)phenol, (II), and 4-(4,5-dihydro-1,3-oxazol-2-yl) phenol, (III)]. In these compounds, the deviation from coplanarity of the oxazoline and benzene rings is dependent on the position of the hydroxy group on the benzene ring. The coplanar arrangement in (I) is stabilized by a strong intramolecular O-H...N hydrogen bond. Surprisingly, the 2-oxazoline ring in molecule B of (II) adopts a 3T4 (C2T C3) conformation, while the 2-oxazoline ring in molecule A, as well as that in (I) and (III), is nearly planar, as expected. Tetramers of molecules of (II) are formed and they are bound together via weak C-H...N hydrogen bonds. In (III), strong intermolecular O-H...N hydrogen bonds and weak intramolecular C-H...O hydrogen bonds lead to the formation of an infinite chain of molecules perpendicular to the b direction. This paper also reports a theoretical investigation of hydrogen bonds, based on density functional theory (DFT) employing periodic boundary conditions.