90149-62-5

Basic information

• Product Name: Hexadecanoic acid, 4-methoxyphenyl ester
• CAS NO: 90149-62-5
• Molecular Formula: C23H38O3
• Molecular Weight: 362.553
• Mol File: 90149-62-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Hexadecanoic acid, 4-methoxyphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Hexadecanoic acid, 4-methoxyphenyl ester(90149-62-5)
• EPA Substance Registry System: Hexadecanoic acid, 4-methoxyphenyl ester(90149-62-5)

Safety Data

• Hazardous Substances Data: 90149-62-5(Hazardous Substances Data)

Upstream product

• 150-76-5 4-methoxy-phenol 
• 57-10-3 1-hexadecylcarboxylic acid 
• 112-67-4 n-hexadecanoyl chloride 

Downstream Products

• 150-76-5 4-methoxy-phenol 
• 57-10-3 1-hexadecylcarboxylic acid 

Relevant articles and documents

Ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o -NosylOXY): A recyclable coupling reagent for racemization-free synthesis of peptide, amide, hydroxamate, and ester

Ubiquitousness of amide and ester functionality makes coupling reactions extremely important. Although numerous coupling reagents are available, methods of preparation of the common and efficient reagents are cumbersome. Those reagents generate a substantial amount of chemical waste and lack recyclability. Ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY), the first member of a new generation of coupling reagents, produces byproducts that can be easily recovered and reused for the synthesis of the same reagent, making the method more environmentally friendly and cost-effective. The synthesis of amides, hydroxamates, peptides, and esters using this reagent is described. The synthesis of the difficult sequences, for example, the islet amyloid polypeptide (22-27) fragment (with a C-terminal Gly, H-Asn-Phe-Gly-Ala-Ile-Leu-Gly-NH 2) and acyl carrier protein (65-74) fragment (H-Val-Gln-Ala-Ala-Ile- Asp-Tyr-Ile-Asn-Gly-OH), following the solid-phase peptide synthesis (SPPS) protocol and Amyloid β (39-42) peptide (Boc-Val-Val-IIe-Ala-OMe), following solution-phase strategy is demonstrated. Remarkable improvement is noticed with respect to reaction time, yield, and retention of stereochemistry. A mechanistic investigation and recyclability are also described.

the Effect of Hydrophobic-Lipophilic Interactions on Chemical Reactivity. 1. New Evidence for Intermolecular Aggregation and Self-Coiling

The hydrolytic behavior of 21 para-substituted phenyl esters of n-alkanoic acids (n-X) with various chain lengths in 60:40 (Φ=0.60), 50:50 (Φ=0.50), and 40:60 v/v (Φ=0.40) Me2SO-H2O mixtures was studied.Four new sets of experimental results which include departure from Hammett correlation for N-hexadecanoates (16-X), substantial differences in activation parameters, and effects of amylose on the kinetic parameters and on the activation parameters are presented along lines of reasoning mentioned by previous authors.These data establish that the aggregation and self-coiling of the n-alkanoate chain actually exist under experimental conditions.