90150-99-5

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 326480-54-0 2-(5-bromo-2-methoxy-phenylsulfanylmethyl)-benzonitrile 

Relevant academic research and scientific papers

Facile introduction of SH group on aromatic substrates via electrophilic substitution reactions

Herein, we describe a mild and efficient two-step procedure to introduce a thiol group on aromatic substrates. First, reaction with an activated sulfoxide leads to an arylsulfonium salt intermediate. Then, two successive β-elimination-based dealkylation reactions afford the desired arylthiols in good to excellent yields.