901535-05-5Relevant academic research and scientific papers
Antimicrobial N-(2-chlorobenzyl)-substituted hydroxamate is an inhibitor of 1-deoxy-d-xylulose 5-phosphate synthase
Hayashi, Daisuke,Kato, Nobuo,Kuzuyama, Tomohisa,Sato, Yasuo,Ohkanda, Junko
, p. 5535 - 5537 (2013)
N-(2-Chlorobenzyl)-substituted hydroxamate, readily produced by hydrolysis of ketoclomazone, was identified as an inhibitor of 1-deoxy-d-xylulose 5-phosphate synthase (DXS), with an IC50 value of 1.0 μM. The compound inhibited the growth of Haemophilus influenzae. A convenient spectroscopic method for assaying DXS using NADPH-lactate dehydrogenase (LDH) is also reported.
Pd-catalyzed decarboxylative ortho-acylation of O-methyl oximes with phenylglyoxylic acids
Yang, Zhiyong,Chen, Xiang,Liu, Jidan,Gui, Qingwen,Xie, Kai,Li, Miaomiao,Tan, Ze
supporting information, p. 1560 - 1562 (2013/03/13)
Aryl ketones were synthesized via Pd-catalyzed decarboxylative coupling between O-methyl oximes and phenylglyoxylic acids using (NH4) 2S2O8 as the oxidant. The Royal Society of Chemistry 2013.
