90167-35-4

Basic information

• Product Name: 4-Amino-1H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile
• Synonyms: 4-Amino-1H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile
• CAS NO: 90167-35-4
• Molecular Formula: C₈H₈N₆
• Molecular Weight: 160.13616
• Mol File: 90167-35-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Amino-1H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-1H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile(90167-35-4)
• EPA Substance Registry System: 4-Amino-1H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile(90167-35-4)

Safety Data

• Hazardous Substances Data: 90167-35-4(Hazardous Substances Data)

Upstream product

• 54385-49-8 5-amino-1H-pyrazole-3,4-dicarbonitrile 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 

Relevant articles and documents

REACTION OF 4-CYANO-5-AMINOPYRAZOLE AND 3,4-DICYANO-5-AMINOPYRAZOLE WITH DIMETHYLFORMAMIDE DIETHYLACETAL

The condensation of 4-cyano-5-aminopyrazole or 3,4-dicyano-5-aminopyrazole with dimethylformamide diethylacetal was studied.It was shown that, in addition to the formation of dimethylaminomethyleneamino derivatives, alkylation of the pyrazole ring occurs under severe conditions without a solvent.Only the corresponding formamidino derivatives are formed when the same reactions are carried out in methanol under milder conditions.The site of addition of an ethyl group to the pyrazole ring in the N-alkyl derivatives obtained was established by 13C NMR and PMR spectroscopy.The possibility of the synthesis of 4-amino- or 4-methylmercaptopyrazolopyrimidines by cyclization of the ortho position was demonstrated for the first time.