90176-39-9

Basic information

• Product Name: 2-benzylideneamino-2-deoxy-β-D-glucopyranose
• Synonyms: 2-benzylideneamino-2-deoxy-β-D-glucopyranose
• CAS NO: 90176-39-9
• Molecular Weight: 267.282
• Mol File: 90176-39-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-benzylideneamino-2-deoxy-β-D-glucopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzylideneamino-2-deoxy-β-D-glucopyranose(90176-39-9)
• EPA Substance Registry System: 2-benzylideneamino-2-deoxy-β-D-glucopyranose(90176-39-9)

Safety Data

• Hazardous Substances Data: 90176-39-9(Hazardous Substances Data)

Upstream product

• 14131-63-6 D-glucosamine hydrochloride 
• 100-52-7 benzaldehyde 
• 1078691-95-8 (+)-D-glucosamine hydrochloride 

Downstream Products

• 85065-26-5 4,6-O-benzylidene-2-benzylideneamino-2-deoxy-β-D-glucopyranose 
• 5432-46-2 acetyl 3,4,6-tri-O-acetyl-2-amino-2-deoxy-D-glucopyranoside hydrochloride 
• 384834-91-7 tetra-O-acetyl-2-(3-nitro-benzoylamino)-2-deoxy-β-D-glucopyranose 
• 10385-49-6 1,2,4,6-tetra-O-acetyl-2-benzamido-2-deoxy-β-D-glucopyranose 
• 5432-46-2 1,3,4,6-tetra-O-acetyl-D-glucosamine hydrochloride 
• 56644-75-8 1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroacetamido)-β-D-glucopyranose 
• 85065-28-7 1,3-di-O-acetyl-2-amino-4,6-O-benzylidene-2-deoxy-β-D-glucopyranose hydrochloride 
• 85065-29-8 2-<(3R)-3-acetoxytetradecanamido>-1,3-di-O-acetyl-4,6-O-benzylidene-2-deoxy-β-D-glucopyranose 
• 85065-27-6 1,3-di-O-acetyl-4,6-O-benzylidene-2-benzylideneamino-2-deoxy-β-D-glucopyranose 
• 85065-33-4 2-<(3R)-3-acetoxytetradecanamido>-6-O-<2-<(3R)-3-acetoxatetradecanamido>-3,6-di-O-acetyl-2-deoxy-4-O-diphenylphosphono-β-D-glucopyranosyl>-1,3-di-O-acetyl-2-deoxy-β-D-glucopyranose 
• 85071-05-2 2-<(3R)-3-acetoxytetradecanamido>-1,3,6-tri-O-acetyl-2-deoxy-β-D-glucopyranose 4-diphenylphosphate 
• 85065-32-3 2-<(3R)-3-acetoxytetradecanamido>-3,6-di-O-acetyl-2-deoxy-4-O-diphenylphosphono-α-D-glucopyranosyl bromide 
• 90243-21-3 2-<(3RS)-3-acetoxytetradecanamido>-6-O-<2-<(3RS)-3-acetoxatetradecanamido>-3,6-di-O-acetyl-2-deoxy-4-O-diphenylphosphono-β-D-glucopyranosyl>-1,3-di-O-acetyl-2-deoxy-β-D-glucopyranose 
• 88862-76-4 2'-<(2RS)-2-acetoxytridecyl>-3,6-di-O-acetyl-1,2-dideoxy-4-O-diphenylphosphono-α-D-glucopyranoso<2.1-d>-Δ²-oxazoline 

Relevant articles and documents

Design, synthesis and biological evaluation of novel flavone Mannich base derivatives as potential antibacterial agents

Abstract: A series of novel Mannich base derivatives of flavone containing benzylamine moiety was synthesized using the Mannich reaction. The results of antifungal activity are not ideal, but its antifungal effect has a certain increase compared to flavonoids. After that, four bacteria were used to test antibacterial experiments of these compounds; compound 5g (MIC = 0.5, 0.125?mg/L) showed significant inhibitory activity against Staphylococcus aureus and Salmonella gallinarum compared with novobiocin (MIC = 2, 0.25?mg/L). Compound 5s exhibited broad spectrum antibacterial activity (MIC = 1, 0.5, 2, 0.05?mg/L) against four bacteria. The selected compounds 5g and 5s exhibit potent inhibition against Topo II and Topo IV with IC50 values (0.25–16?mg/L). Molecular docking model showed that the compounds 5g and 5s can bind well to the target by interacting with amino acid residues. It will provide some valuable information for the commercial antibacterial agents. Graphical Abstract: [Figure not available: see fulltext.].

Prednisolone succinate-glucosamine conjugate: Synthesis, characterization and in vitro cellular uptake by kidney cell lines

Prednisolone succinate-glucosamine (PSG) conjugate, a prodrug for prednisolone, was synthesized and confirmed by NMR and MS spectrum. The stabilities of the prodrug in PBS (pH 2.50, 5.00, 7.20, and 7.89) were studied. Cytotoxicity and uptake assay of the prodrug were perfomed on HK-2 and MDCK cell lines. The results showed that compared with prednisolone, the PSG not only did not increase the cytotoxicity but also improved the uptake to 2.2 times of prednisolone by the cells. Thus, it indicated that glucosamine might be a potential carrier for kidney-targeting delivery of prednisolone.