901770-40-9Relevant academic research and scientific papers
Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug
El Alaoui, Abdessamad,Schmidt, Frederic,Amessou, Mohamed,Sarr, Marianne,Decaudin, Didier,Florent, Jean-Claude,Johannes, Ludger
, p. 6469 - 6472 (2008/09/17)
(Figure Presented) A retrograde strategy: An innovative cancer-cell delivery concept exploits the naturally evolved characteristics of the Shiga toxin B-subunit (STxB) for the intracellular activation of a newly synthesized prodrug at the level of the bio
