901778-62-9Relevant academic research and scientific papers
New Taxol (paclitaxel) prodrugs designed for ADEPT and PMT strategies in cancer chemotherapy
Alaoui, Abdessamad El,Saha, Nabendu,Schmidt, Frédéric,Monneret, Claude,Florent, Jean-Claude
, p. 5012 - 5019 (2006)
Two new glucuronide paclitaxel prodrugs have been synthesized. Linked to the 2′-OH of the drug by a carbonate function, they include a self-immolative spacer bearing an arylnitro or arylamino group between the drug and the glucuronic acid residue. Both pr
