90198-91-7Relevant academic research and scientific papers
SYNTHESIS OF 5-ALKYL-3H-THIOLEN-2-ONES AND 5-ALKYL-3H-FURAN-2-ONES AND CONDENSATION REACTIONS AT THE HETEROCYCLIC METHYLENE GROUP
Sedavkina, V. A.,Morozova, N. A.,Egorova, A. Yu.,Ostroumov, I. G.
, p. 377 - 380 (1987)
The intramolecular cyclization of γ-ketocarboxylic acids and their esters gives 5-alkylsubstituted 3H-thiolen-2-ones and 3H-furan-2-ones.It was shown that reaction occured at the heterocyclic methylene group and that the conditions under which the reaction took place depended on the nature of the heterocyclic atom.
Thionylation of 5-alkyl-3H-furan-2-ones and their non-cyclic 4-oxoalkanoate ester analogs
Egorova,Sedavkina,Morozova
, p. 41 - 44 (2007/10/03)
We have studied thionylation of 5-R-3H-furan-2-ones and 4-oxoalkanoates using phosphorus pentasulfide and the Lawesson reagent. It was found that the structure of the reaction products depended on the thionylating agent. Preparative methods have been developed for the synthesis of 5-R-5H- and 5-R-3H-thiophen-2-ones and 5-R-3H-furan-2-thiones. 1999 KluwerAcademic/Plenum.
