Chemistry of Heterocyclic Compounds p. 377 - 380 (1987)
Update date:2022-08-02
Topics:
Sedavkina, V. A.
Morozova, N. A.
Egorova, A. Yu.
Ostroumov, I. G.
The intramolecular cyclization of γ-ketocarboxylic acids and their esters gives 5-alkylsubstituted 3H-thiolen-2-ones and 3H-furan-2-ones.It was shown that reaction occured at the heterocyclic methylene group and that the conditions under which the reaction took place depended on the nature of the heterocyclic atom.
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