902452-74-8

Basic information

• Product Name: 7-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-2-N-dimethylaminomethyleneguanine
• Synonyms: 7-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-2-N-dimethylaminomethyleneguanine
• CAS NO: 902452-74-8
• Molecular Weight: 652.707
• Mol File: 902452-74-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-2-N-dimethylaminomethyleneguanine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-2-N-dimethylaminomethyleneguanine(902452-74-8)
• EPA Substance Registry System: 7-[5-O-(4,4'-dimethoxytrityl)-2-O,4-C-methylene-β-D-ribofuranosyl]-2-N-dimethylaminomethyleneguanine(902452-74-8)

Safety Data

• Hazardous Substances Data: 902452-74-8(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 709641-80-5 (1R,3R,4R,7S)-7-benzyloxy-1-methanesulfonyloxymethyl-3-(2-N-isobutyrylguanin-7-yl)-2,5-dioxabicyclo[2.2.1]heptane 
• 293751-03-8 1,2-di-O-acetyl-3-O-benzyl-4-C-methanesulfonyloxymethyl-5-O-methanesulfonyl-D-erythro-pentofuranose 
• 21047-89-2 2-N-isobutyrylguanine 
• 902452-68-0 7-(2-O-acetyl-3-O-benzyl-4-C-methanesulfonyloxy-5-O-methanesulfonyl-β-D-erythro-pentofuranosyl)-2-N-isobutyrylguanine 
• 902452-69-1 7-(5-O-benzoyl-3-O-benzyl-2-O,4-C-methylene-β-D-ribofuranosyl)-2-N-isobutyrylguanine 
• 902452-70-4 7-(3-O-benzyl-2-O,4-C-methylene-β-D-ribofuranosyl)-2-N-isobutyrylguanine 
• 902452-71-5 N-[7-(7-hydroxy-1-hydroxymethyl-2,5-dioxa-bicyclo[2.2.1]hept-3-yl)-6-oxo-6,7-dihydro-1H-purin-2-yl]-isobutyramide 
• 902452-73-7 7-(2-O,4-C-methylene-β-D-ribofuranosyl)guanine 

Relevant articles and documents

Conformationally restricted triplex-forming oligonucleotides (TFOs). Binding properties of α-l-LNA and introduction of the N7-glycosylated LNA-guanosine

The method for scaled-up production of α-l-LNA phosphoramidite building blocks containing thymine and 5-methylcytosine nucleobases is described. Binding properties of pyrimidine TFOs modified with α-l-LNA are reported. In contrast to LNA TFOs, the fully m