90246-79-0Relevant academic research and scientific papers
3-Alkyl-8-chloro-5,6-dihydrofuro-[3,2-f]-1,2-benzisoxazole-6-carboxylic acids
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, (2008/06/13)
Disclosed are compounds of the formula: STR1 wherein X is hydrogen, loweralkyl, loweralkoxy or halo, Y is hydroxymethyl, carboxyl, carboxamido or carboloweralkoxy, and R is cyclohexyl, benzyl, norbornyl, loweralkyl, or a pharmaceutically acceptable salt thereof. The compounds are effective as diuretic agents.
Benzisoxazole carboxylic acids
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, (2008/06/13)
Described are compounds of the formula STR1 wherein X is hydrogen, loweralkyl, halo, loweralkoxy or trifluoromethyl, and Z is hydrogen, loweralkyl, halo, hydroxy or alkoxy, or compounds of the formula STR2 wherein X' and Y' may be the same or different an
Benzisoxazole carboxylic acids
-
, (2008/06/13)
Described are compounds of the formula STR1 wherein X is hydrogen, loweralkyl, halo, loweralkoxy or trifluoromethyl, and Z is hydrogen, loweralkyl, halo, hydroxy or alkoxy, or compounds of the formula STR2 wherein X' and Y' may be the same or different an
Substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazole-6-carboxylic acids: High-ceiling diuretics with uricosuric activity
Plattner,Fung,Parks,et al.
, p. 1016 - 1026 (2007/10/02)
A series of substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazoles was prepared and evaluated for their saluretic and uricosuric properties. Pharmacological evaluation of the title compounds was carried out in mice, rats, dogs, and monkeys. The diuretic/sa
