90252-89-4

Basic information

• Product Name: Zinc, chloro(4-methylphenyl)-
• Synonyms: 4-methylphenylzinc chloride;p-TolylZnCl;ZINC, CHLORO(4-METHYLPHENYL)-;Zinc,chloro(4-methylphenyl);4-methylphenyl-ZnCl;p-tolylzinc(II) chloride;p-MeC6H4ZnCl
• CAS NO: 90252-89-4
• Molecular Formula: C7H7ClZn
• Molecular Weight: 191.976
• Mol File: 90252-89-4.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Zinc, chloro(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, chloro(4-methylphenyl)-(90252-89-4)
• EPA Substance Registry System: Zinc, chloro(4-methylphenyl)-(90252-89-4)

Safety Data

• Hazardous Substances Data: 90252-89-4(Hazardous Substances Data)

Upstream product

• 4294-57-9 para-methylphenylmagnesium bromide 
• 106-38-7 para-bromotoluene 
• 7439-95-4 magnesium 
• 7646-85-7 zinc(II) chloride 
• 2417-95-0 p-tolyllithium 

Downstream Products

• 4999-58-0 1-methyl-4-(6-methylhepta-1,5-dien-2-yl)benzene 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 613-33-2 (4,4'-dimethyl-1,1'-biphenyl) 
• 106-49-0 p-toluidine 
• 104-94-9 4-methoxy-aniline 
• 31006-98-1 1-(3,3-dimethylbut-1-en-2-yl)-4-methylbenzene 
• 142039-30-3 (E)-1-(3,3-dimethylbut-1-en-1-yl)-4-methylbenzene 
• 1093686-53-3 1-(1-cyclohexylvinyl)-4-methylbenzene 
• 61153-38-6 (E)-1-(2-cyclohexylvinyl)-4-methylbenzene 
• 62882-04-6 2-(p-tolyl)oxazole 
• 50670-50-3 p-(p-tolyl)benzonitrile 
• 644-08-6 4-Methylbiphenyl 
• 4467-06-5 2-(4-methylphenyl)pyridine 
• 53040-92-9 4-(4-tolyl)anisole 

Relevant articles and documents

Directed Zincation or Magnesiation of the 2-Pyridone and 2,7-Naphthyridone Scaffold Using TMP Bases

A regioselective zincation of the 2-pyridone and 2,7-naphthyridone scaffolds has been developed. Zincations of the methoxyethoxymethyl (MEM)-protected compounds using TMP2Zn·2MgCl2·2LiCl (TMP = 2,2,6,6-tetramethylpiperidyl) followed

The Formation of P-C Bonds Utilizing Organozinc Reagents for the Synthesis of Aryl- A nd Heteroaryl-Dichlorophosphines

Aryl- A nd heteroaryl-dichlorophosphines are mildly and selectively made in a one-pot synthesis in moderate to good yields starting from the respective aryl bromides or five-membered heterocycles, following lithiation with nBuLi, transmetalation with ZnCl

Asymmetric Synthesis of Alkylzincs by Rhodium-Catalyzed Enantioselective Arylative Cyclization of 1,6-Enynes with Arylzincs

A chiral diene-rhodium complex was found to catalyze the reaction of 1,6-enynes with ArZnCl to give high yields of 2-(alkylidene)cyclopentylmethylzincs with high enantioselectivity (95–99 % ee). The enantioenriched alkylzincs were readily converted in a one-pot approach into a wide variety of functionalized products by taking advantage of their unique reactivity. The catalytic cylcle involves arylrhodation of alkyne, intramolecular alkenylrhodation of alkene, and transmetalation of the alkyl-rhodium intermediate into alkylzinc.