90280-13-0

Basic information

• Product Name: BisfluoroModafinil
• Synonyms: BisfluoroModafinil;FlModafinil;CRL-40,940;CRL-40,90;2-[[Bis(4-fluorophenyl)methyl]sulfinyl]acetamide;Acetamide, 2-[[bis(4-fluorophenyl)methyl]sulfinyl]-;CRL-40,940/Flmodafinil
• CAS NO: 90280-13-0
• Molecular Formula: C₁₅H₁₃F₂NO₂S
• Molecular Weight: 309.3310264
• EINECS: -0
• Mol File: 90280-13-0.mol

Chemical Properties

• Melting Point: 78-80 °C
• Boiling Point: 558.7±50.0 °C(Predicted)
• Appearance: /
• Density: 1.397±0.06 g/cm3(Predicted)
• PKA: 14.82±0.40(Predicted)
• CAS DataBase Reference: BisfluoroModafinil(CAS DataBase Reference)
• NIST Chemistry Reference: BisfluoroModafinil(90280-13-0)
• EPA Substance Registry System: BisfluoroModafinil(90280-13-0)

Safety Data

• Hazardous Substances Data: 90280-13-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
BisfluoroModafinil is used as a therapeutic agent for treating attention deficit disorders, sleep disorders, and mild depression. Its ability to improve cognitive function and motivation makes it a valuable asset in managing these conditions.
Used in Cognitive Enhancement:
BisfluoroModafinil is used as a cognitive enhancer to improve brain power and problem-solving abilities. Its nootropic properties make it an effective tool for individuals seeking to optimize their mental performance.
Used in Neuroprotection:
BisfluoroModafinil is used as a neuroprotective agent to shield the brain from chemical or physical injuries. This quality makes it a potential candidate for the prevention and treatment of neurodegenerative diseases and conditions that involve brain damage.

Upstream product

• 460-00-4 1-Bromo-4-fluorobenzene 
• 459-57-4 4-fluorobenzaldehyde 
• 90280-19-6 C₁₄H₁₂F₂N₂S*BrH 
• 365-24-2 4,4'-difluorobenzhydryl alcohol 
• 90212-81-0 2-((bis(4-fluorophenyl)methyl)-thio)acetic acid 
• 90280-20-9 2-(bis(4-fluorophenyl)methylthio)acetamide 
• 90212-82-1 methyl [[bis-(4-fluorophenyl)methyl]thio]acetate 

Relevant articles and documents

LAUFLUMIDE AND THE ENANTIOMERS THEREOF, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF

The invention relates to the molecule having formula (I), as well as the enantiomers thereof, and to the use of same in the treatment of ADHD, narcolepsy or idiopathic hypersomnia.

SARs at the monoamine transporters for a novel series of modafinil analogues

A series of modafinil (1) analogues were synthesized wherein (1) para-halo-substitutents were added to the aryl rings, (2) the sulfoxide function was removed, and (3) the primary amide group was replaced with secondary and tertiary amides and amines to investigate the effects of these chemical modifications on dopamine transporter, serotonin transporter, and norepinephrine transporter binding. In addition, the locomotor-stimulant effects in mice of (±)-modafinil (1), its R-and S-enantiomers, and its para-chloro sulfinylacetamide analogue (5c) were compared to those of cocaine.