902837-26-7 Usage
Uses
Used in Pharmaceutical Synthesis:
4-Pyrrolidin-1-yl-piperidine-1-carboxylic acid tert-butyl ester is used as a key intermediate in the synthesis of various pharmaceuticals due to its ability to enhance the chiral properties of the resulting compounds, which is crucial for the development of enantiomerically pure drugs.
Used in Organic Chemistry:
In the field of organic chemistry, 4-Pyrrolidin-1-yl-piperidine-1-carboxylic acid tert-butyl ester is used as a ligand and a chiral auxiliary for facilitating asymmetric reactions, leading to the production of enantiomerically enriched products.
Used in the Creation of Heterocyclic Compounds:
4-Pyrrolidin-1-yl-piperidine-1-carboxylic acid tert-butyl ester is utilized as a building block in the synthesis of heterocyclic compounds, which are important in medicinal chemistry and have a wide range of biological activities.
Used as a Reagent in Organic Synthesis:
4-PYRROLIDIN-1-YL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is employed as a reagent in the creation of complex organic molecules, where its unique structure and functional groups contribute to the formation of desired products with high selectivity and yield.
Used in Research and Development:
4-Pyrrolidin-1-yl-piperidine-1-carboxylic acid tert-butyl ester is also used in research and development settings to explore new synthetic pathways and to develop innovative methods for the synthesis of biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 902837-26-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,2,8,3 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 902837-26:
(8*9)+(7*0)+(6*2)+(5*8)+(4*3)+(3*7)+(2*2)+(1*6)=167
167 % 10 = 7
So 902837-26-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H26N2O2/c1-14(2,3)18-13(17)16-10-6-12(7-11-16)15-8-4-5-9-15/h12H,4-11H2,1-3H3
902837-26-7Relevant academic research and scientific papers
Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor
Nencini, Arianna,Castaldo, Cristiana,Comery, Thomas A.,Dunlop, John,Genesio, Eva,Ghiron, Chiara,Haydar, Simon,Maccari, Laura,Micco, Iolanda,Turlizzi, Elisa,Zanaletti, Riccardo,Zhang, Jean
, p. 401 - 418 (2014/04/17)
α7 nicotinic acetylcholine receptor agonists are promising therapeutic candidates for the treatment of cognitive impairment. As a follow up of our internal medicinal chemistry program we investigated a novel series of α7 nAChR agonists. Starting from molecular docking studies on two series of molecules recently developed in our laboratories, an alternative scaffold was designed attempting to combine the optimal features of these previously identified urea and pyrazole compounds. Based on our previous SAR knowledge and on predicted drug-like properties, a small library was synthesized in parallel manner, affording compounds with excellent α7 nAChR activity, selectivity and preliminary ADME profile.
