90295-51-5

Basic information

• Product Name: (+/-)-trans-5-methoxy-1-methyl-2-(α-propylamino)tetralin
• CAS NO: 90295-51-5
• Molecular Weight: 233.354
• Mol File: 90295-51-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-trans-5-methoxy-1-methyl-2-(α-propylamino)tetralin(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-trans-5-methoxy-1-methyl-2-(α-propylamino)tetralin(90295-51-5)
• EPA Substance Registry System: (+/-)-trans-5-methoxy-1-methyl-2-(α-propylamino)tetralin(90295-51-5)

Safety Data

• Hazardous Substances Data: 90295-51-5(Hazardous Substances Data)

Upstream product

• 90295-48-0 trans-2-amino-5-methoxy-1-methyltetralin 
• 42263-75-2 1-methyl-5-methoxy-2-tetralone 
• 90295-50-4 N-((1S,2S)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide 
• 90295-58-2 5-methoxy-1-methyl-2-tetralone oxime 
• 90295-47-9 1,2-dihydro-4-methyl-8-methoxynaphthalene 
• 33892-75-0 5-Methoxy-1-tetralone 

Relevant articles and documents

C1-Methylated 5-hydroxy-2-(dipropylamino)tetralins: central dopamine-receptor stimulating activity.

C1-Methylated derivatives of the potent dopaminergic agonist 5-hydroxy-2-(di-n-propylamino)tetralin (6) have been synthesized and tested for central dopamine (DA) receptor stimulating activity, by using biochemical and behavioral tests in rats. Both cis- and trans-5-hydroxy-1-methyl-2-(di-n-propylamino) tetralin (4 and 3) may be classified as central DA-receptor agonists, albeit of lower potency than 6. The results obtained indicate that both 4 and 3 display DA-autoreceptor stimulation capacity. However, only one of the isomers, trans-3, is able to elicit clear-cut postsynaptic DA receptor agonist actions at larger doses. 5-Hydroxy-1,1-dimethyl-2-(n-propylamino) tetralin (5) was found to be inactive.