42263-75-2

Basic information

• Product Name: 5-methoxy-1-methyl-3,4-dihydronaphthalen-2(1H)-one
• CAS NO: 42263-75-2
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.2384
• Mol File: 42263-75-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 321.6°C at 760 mmHg
• Flash Point: 146.3°C
• Density: 1.076g/cm³
• Vapor Pressure: 0.000295mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: 5-methoxy-1-methyl-3,4-dihydronaphthalen-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxy-1-methyl-3,4-dihydronaphthalen-2(1H)-one(42263-75-2)
• EPA Substance Registry System: 5-methoxy-1-methyl-3,4-dihydronaphthalen-2(1H)-one(42263-75-2)

Safety Data

• Hazardous Substances Data: 42263-75-2(Hazardous Substances Data)

Upstream product

• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 33892-75-0 5-Methoxy-1-tetralone 
• 6099-03-2 3-(2'-methoxyphenyl)propenoic acid 
• 73067-20-6 5-Methoxy-2-oxo-1,2,3,4-tetrahydro-naphthalene-1-carbothioic acid S-methyl ester 
• 575-44-0 1,6-dihydroxynaphthalene 
• 105372-18-7 1,2,3,4-tetrahydro-1,2-methano-2,5-dimethoxynaphthalene 
• 32940-15-1 5-methoxy-2-tetralone 
• 73739-49-8 5-Methoxy-1-methyl-2-oxo-1,2,3,4-tetrahydronaphthalin-1-thiocarbonsaeuremethylester 
• 90295-47-9 1,2-dihydro-4-methyl-8-methoxynaphthalene 

Downstream Products

• 5720-82-1 8-methoxy-4a-methyl-4,4a,9,10-tetrahydro-3H-phenanthren-2-one 
• 120303-35-7 (5-Methoxy-1-methyl-3,4-dihydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-amine 
• 79548-61-1 (3bR,9bS)-6-hydroxy-7-isopropyl-9b-methyl-3b,4,10,11-tetrahydrophenanthro[1,2-c]furan-1,5(3H,9bH)-dione 
• 5095-09-0 (+/-)-Δ¹⁶-Kauren-19-saeure 
• 90295-51-5 (+/-)-trans-5-methoxy-1-methyl-2-(α-propylamino)tetralin 
• 95999-15-8 (-)-cis-5-methoxy-1-methyl-2-<(1-phenylethyl)amino>tetralin 
• 95999-17-0 (1S,2R,αR)-cis-5-methoxy-2-<(α-phenylethyl)amino>tetralin 

Relevant articles and documents

Synthesis of 2-tetralone derivatives by Bi(OTf)3-catalyzed intramolecular hydroarylation/isomerization of propargyl alcohols

Compared to 1-tetralones, 2-tetralones are expensive, less stable, and difficult to synthesize. A concise Bi-catalyzed method was developed for the synthesis of 2-tetralones from 5-phenylpent-1-yn-3-ol derivatives. Diverse 2-tetralones were obtained in moderate to good yields under mild conditions.

An unexpected double-bond isomerization catalyzed by Crabtree's iridium(I) catalyst

The first iridium-catalyzed isomerization of an exocyclic into an endocyclic double bond is described. A mechanism is proposed for this reaction. Crabtree's catalyst thus allows the migration of a double bond that does not occur under classical conditions. Georg Thieme Verlag Stuttgart.

Facile Synthesis of 5-Methoxy-3-methyl-2-tetralone

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