90312-01-9

Basic information

• Product Name: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-nitro-
• CAS NO: 90312-01-9
• Molecular Formula: C13H12N2O5S
• Molecular Weight: 308.315
• Mol File: 90312-01-9.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-nitro-(90312-01-9)
• EPA Substance Registry System: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-nitro-(90312-01-9)

Safety Data

• Hazardous Substances Data: 90312-01-9(Hazardous Substances Data)

Upstream product

• 118-92-3 anthranilic acid 
• 5344-90-1 2-Aminobenzyl alcohol 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 

Downstream Products

• 1589599-37-0 (3S)-3-(2-chlorophenyl)-4-methyl-1-[(4-nitrobenzene)sulfonyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine 
• 1589599-39-2 C₂₁H₂₇N₃O₄S 
• 1589599-42-7 (2R)-N,4-bis[(4-methoxyphenyl)methyl]-1-[(4-nitrobenzene)sulfonyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2-carboxamide 
• 601481-97-4 N-(4'-nitrobenzenesulfonyl)-o-aminobenzaldehyde 

Relevant articles and documents

Asymmetric [4+2] cycloaddition of azlactones with dipolar copper–allenylidene intermediates for chiral 3,4-dhydroquinolin-2-one derivatives

In this paper, a pybox-copper catalyzed enantioselective decarboxylative [4+2] cycloaddition reaction of ethynyl benzoxazinanones with azlactones has been developed, which provides optically active 3,4-dihydroquinolin-2-ones in high yields with good enantioselectivities and diastereoselectivities. In this transformation, the chiral dipolar copper–allenylidene intermediates are kinetically generated via decarboxylative ethynyl benzoxazinanones, followed by the attack of the enolate azlactones to form enantiomerically enriched 3,4-dihydroquinolin-2-one structures.

Enantioselective Synthesis of Complex Fused Heterocycles through Chiral Phosphoric Acid Catalyzed Intramolecular Inverse-Electron-Demand Aza-Diels–Alder Reactions

A stable asymmetric intramolecular Povarov reaction has been established to provide an efficient method to access structurally diverse trans,trans-trisubstituted tetrahydrochromeno[4,3-b]quinolines in high stereoselectivities of up to >99:1 diastereomeric

Iridium- and Rhodium-Catalyzed Directed C-H Heteroarylation of Benzaldehydes with Benziodoxolone Hypervalent Iodine Reagents

The C-H heteroarylation of benzaldehydes with indoles and pyrroles was realized using the benziodoxolone hypervalent iodine reagents indole- and pyrroleBX. Functionalization of the aldehyde C-H bond using either an o-hydroxy or amino directing group and catalyzed by an iridium or a rhodium complex allowed the synthesis of salicyloylindoles and (2-sulfonamino)benzoylindoles, respectively, with good to excellent yields (74-98%). This new transformation could be carried out under mild conditions (rt to 40 °C) and tolerated a broad range of functionalities, such as ethers, halogens, carbonyls, or nitro groups.