90340-75-3Relevant academic research and scientific papers
An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization
Folgueiras-Amador, Ana A.,Philipps, Kai,Guilbaud, Sébastien,Poelakker, Jarno,Wirth, Thomas
supporting information, p. 15446 - 15450 (2017/11/10)
Flow electrochemistry is an efficient methodology to generate radical intermediates. An electrochemical flow microreactor has been designed and manufactured to improve the efficiency of electrochemical flow reactions. With this device only little or no supporting electrolytes are needed, making processes less costly and enabling easier purification. This is demonstrated by the facile synthesis of amidyl radicals used in intramolecular hydroaminations to produce isoindolinones. The combination with inline mass spectrometry facilitates a much easier combination of chemical steps in a single flow process.
Intramolecular Hydroamidation of ortho-Vinyl Benzamides Promoted by Potassium tert-Butoxide/N,N-Dimethylformamide
Chen, Zhen-Yu,Wu, Liang-Yu,Fang, Hai-Sheng,Zhang, Ting,Mao, Zhi-Feng,Zou, Yong,Zhang, Xue-Jing,Yan, Ming
supporting information, p. 3894 - 3899 (2017/10/07)
An intramolecular hydroamidation of ortho-vinyl benzamides had been developed. The reaction was promoted efficiently by potassium tert-butoxide and N,N-dimethylformamide without the need for strong oxidants or transition-metal catalysts. A series of dihyd
Selenium-mediated synthesis of biaryls through rearrangement
Shahzad, Sohail A.,Vivant, Clotilde,Wirth, Thomas
supporting information; experimental part, p. 1364 - 1367 (2010/06/17)
"Chemical Equation Presented" A new cyclization of β-keto ester substituted stilbene derivatives using selenium electrophiles in the presence of Lewis acids is described. Substituted naphthols are obtained through cyclization and subsequent 1,2-rearrangement of aryl groups under very mild reaction conditions.
Diselenide- and disulfide-mediated synthesis of isocoumarins
Shahzad, Sohail A.,Venin, Claire,Wirth, Thomas
experimental part, p. 3465 - 3472 (2010/09/07)
Cyclizations of stilbenecarboxylic acids to the corresponding isocoumarin derivatives using diselenide or disulfide reagents have been developed. By employing bis(triflouroacetoxy)iodobenzene as oxidant for the 6-endo-trig cyclizations a variety of dihydroisocoumarins have been prepared in good yields. This method is capable of forming isocoumarins and dihydroisocoumarin derivatives by a cyclization-elimination route.
The Photochemistry of Alkyl 2-(Naphthalenyl)ethenylbenzoates:Photodehydrocyclization and Photodimerization Products and Their Structural Elucidation by 1H and 13C N.M.R.
Jones, Alan J.,Teitei, Tsutomu
, p. 561 - 576 (2007/10/02)
Irradiation of alkyl 2-benzoates in benzene gave the photodehydrocyclization product, the chrysenecarboxylates (3) as well as two of the photodimerization products, the cyclobutanes (6) and (7).Similarly, irradiation of alkyl 2
