90349-77-2

Upstream product

• 75-44-5 phosgene 
• 92504-03-5 N-(2-aminoethyl)-2-nitrobenzenesulfonamide hydrochloride 
• 214000-16-5 N-(tert-butoxycarbonyl)-N'-(2-nitrobenzenesulfonyl)ethylenediamine 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 

Downstream Products

• 1206703-09-4 C₂₀H₂₆N₄O₅S 
• 1206703-08-3 C₁₃H₂₀N₄O₅S 
• 1206703-11-8 C₂₃H₃₂N₆O₆S 
• 1206703-14-1 C₂₇H₄₀N₈O₇S 

Relevant academic research and scientific papers

An efficient synthesis of N,N'-linked oligoureas

This paper reports an efficient synthesis of N-alkyl-N,N'-linked oligourcas [-NR-CO-NH-CH2CH2](n), which involves the repetition of three steps: (1) main-chain extension by ring-opening of N-(2- nitrobenzenesulfonyl)-2-imidazolidone (1) by a secondary amine RR'NH to afford sulfonamide RR'N-CO-NH-CH2CH2-NH-SO2Ar (2) side-chain attachment by N-alkylation of the sulfonamide with alkyl halide R'X, and (3) removal of the sulfonyl group to give a new secondary amine RR'N-CO NH-CH2CH2-NHR'). A tetraurea was prepared in 10 steps and 58% overall yield by this method.