903550-13-0Relevant academic research and scientific papers
Palladium-catalysed direct diarylations of pyrazoles with aryl bromides: A one step access to 4,5-diarylpyrazoles
Takfaoui, Abdelilah,Zhao, Liqin,Touzani, Rachid,Dixneuf, Pierre H.,Doucet, Henri
, p. 1697 - 1701 (2014/03/21)
The palladium-catalysed direct arylation of pyrazoles with aryl halides, using PdCl(C3H5)(dppb)/KOAc catalyst, reveals a similar reactivity of C4 and C5 CH bonds of pyrazoles, whereas the C3 CH bond is almost unreactive, and gives ac
C-H bonds as ubiquitous functionality: A general approach to complex arylated pyrazoles via sequential regioselective C-arylation and N-alkylation enabled by SEM-group transposition
Goikhman, Roman,Jacques, Teresa L.,Sames, Dalibor
supporting information; experimental part, p. 3042 - 3048 (2009/09/04)
Pyrazoles are important azole heteroarenes frequently found in pharmaceuticals and protein ligands, and there has been a growing interest in newsynthetic methods for their preparation. We report the first catalytic intermolecular C-H arylation of pyrazole
Efficient and simple synthesis of 3-aryl-1H-pyrazoles
Gérard, Anne-Laure,Bouillon, Alexandre,Mahatsekake, Clément,Collot, Valérie,Rault, Sylvain
, p. 4665 - 4669 (2007/10/03)
Efficient preparation of 3-aryl-1H-pyrazoles by reaction of 1-protected-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoles with (het)aryl halides is described. The choice of THP protecting group is discussed.
