903557-29-9

Usage

Uses

Used in Organic Chemistry:
(S)-5-BROMO-2,3-DIHYDRO-1H-INDEN-1-AMINE is used as a building block for the synthesis of various organic compounds. Its unique reactivity, due to the presence of the bromine atom, allows for a wide range of chemical reactions, making it a valuable intermediate in the preparation of complex organic molecules.
Used in Pharmaceutical Development:
(S)-5-BROMO-2,3-DIHYDRO-1H-INDEN-1-AMINE is used as a key intermediate in the development of new pharmaceuticals. Its chiral (S)-configuration and unique reactivity make it a promising candidate for the synthesis of enantiomerically pure drug molecules. (S)-5-BROMO-2,3-DIHYDRO-1H-INDEN-1-AMINE can be further modified and functionalized to create novel therapeutic agents with improved efficacy and selectivity.
Used in Drug Synthesis:
(S)-5-BROMO-2,3-DIHYDRO-1H-INDEN-1-AMINE is used as a starting material for the synthesis of various drug molecules. Its unique structure and reactivity enable the development of innovative synthetic routes to access complex drug targets. The bromine atom in the molecule can be selectively replaced or modified, allowing for the introduction of functional groups that can enhance the pharmacological properties of the resulting drug molecules.
Used in Material Science:
(S)-5-BROMO-2,3-DIHYDRO-1H-INDEN-1-AMINE can be used as a building block for the development of new materials with unique properties. The presence of the bromine atom and the aromatic nature of the molecule make it suitable for the synthesis of novel polymers, coatings, and other materials with potential applications in various industries, such as electronics, automotive, and aerospace.

Upstream product

• 1038919-63-9 (R)-5-bromo-2,3-dihydro-1H-inden-1-ol 
• 34598-49-7 5-Bromo-1-indanone 
• 34598-50-0 5-bromo-1-indanol 
• 1038919-64-0 (S)-1-azido-5-bromo-2,3-dihydro-1H-indene 
• 185122-74-1 5-bromo-2,3-dihydro-1H-inden-1-one oxime 

Downstream Products

• 903557-31-3 tert-butyl N-[(S)-5-bromo-2,3-dihydroinden-1-yl]carbamate 

Relevant academic research and scientific papers

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

The invention provides novel compounds having the general Formula (I), wherein R1, R2, R3, R4 R5, R6, R7, R8 R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.

COMPOUNDS HAVING BOTH ANGIOTENSIN II RECEPTOR ANTAGONISM AND PPARY ACTIVATING ACTIVITIES

Compounds of following formula (I) are provided that have both angiontensin Il receptor antagonist activity and PPARy agonist activity. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment of diseases with the co

METALLOPROTEASE INHIBITORS

The present invention relates to amide containing aromatic MMP inhibiting compounds with a mono-amide heteroaromatic group, of formulas I and II:

HETEROBICYCLIC METALLOPROTEASE INHIBITORS

The present invention relates generally to heterobicyclic containing pharmaceutical agents, and in particular, to heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic metalloprotease inhibiting compounds that exhibit an increased potency in relation to currently known metalloprotease inhibitors.

HETEROBICYCLIC METALLOPROTEASE INHIBITORS

The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP- 13 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP- 13 inhibitors.