903563-88-2

Upstream product

• 423157-61-3 1-(2-chlorophenyl)-2-cyanoallyl acetate 
• 108164-67-6 3-(2-chlorophenyl)-3-hydroxy-2-methylenepropionitrile 

Downstream Products

• 903563-95-1 1-[3-(2-chloro-phenyl)-2-cyano-allyl]-3-(2,4-dichloro-phenyl)-urea 
• 903563-97-3 1-(3-chloro-4-methyl-phenyl)-3-[3-(2-chloro-phenyl)-2-cyano-allyl]-urea 
• 903563-96-2 1-[3-(2-chloro-phenyl)-2-cyano-allyl]-3-(3,4-dichloro-phenyl)-urea 
• 903563-98-4 1-[3-(2-chloro-phenyl)-2-cyano-allyl]-3-phenyl-thiourea 
• 903563-94-0 1-(4-chloro-phenyl)-3-[3-(2-chloro-phenyl)-2-cyano-allyl]-urea 

Relevant academic research and scientific papers

Alternate, easy and practical synthesis of allylamines from acetyl derivatives of Baylis-Hillman adducts using methanolic ammonia

A methanolic ammonia-mediated alternate, easy and practical stereoselective synthesis of allylamines from the acetyl derivatives of Baylis-Hillman adducts is described. Georg Thieme Verlag Stuttgart.

Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives

The synthesis of several 1-(2-cyano-3-aryl-allyl)-3-aryl-urea(thiourea) constructed from the reaction between allylamines generated from Baylis-Hillman acetates and substituted isocyanates and isothiocyanates has been described. Further, their cyclization in the presence of a base led to the formation of 5-arylmethyl-4-imino-3-aryl-3,4-dihydro-1H-pyrimidin-2-ones. All compounds were tested for their antibacterial activity. Few of the compounds showed superior activity or were equipotent to the standard antibacterial agents.