903568-77-4

Basic information

• Product Name: C₁₀H₁₂N₆O₆*ClH
• Synonyms: C₁₀H₁₂N₆O₆*ClH
• CAS NO: 903568-77-4
• Molecular Weight: 348.703
• Mol File: 903568-77-4.mol

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₂N₆O₆*ClH(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₂N₆O₆*ClH(903568-77-4)
• EPA Substance Registry System: C₁₀H₁₂N₆O₆*ClH(903568-77-4)

Safety Data

• Hazardous Substances Data: 903568-77-4(Hazardous Substances Data)

Upstream product

• 903568-75-2 O₂-(2,4-dinitrophenyl)-1-[4-(tert-butoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 

Downstream Products

• 1163704-71-9 O₂-(2,4-dinitrophenyl) 1-[4-(vinylcarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1163704-74-2 O₂-(2,4-dinitrophenyl) 1-[4-(propargyloxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1163704-70-8 O₂-(2,4-dinitrophenyl) 1-[4-(2-fluoroethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1163704-78-6 O₂-(2,4-dinitrophenyl) 1-[4-(diethoxyphosphoryl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1163704-77-5 O₂-(2,4-dinitrophenyl) 1-[4-(ethylaminocarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1163704-76-4 O₂-(2,4-dinitrophenyl) 1-[4-(ethylmercaptocarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1163704-73-1 O₂-(2,4-dinitrophenyl) 1-[4-(allyloxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 1012338-86-1 O₂-(2,4-dinitrophenyl) 1-[4-(2,2,2-trichloroethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 
• 205432-12-8 O²-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate 

Relevant articles and documents

Drug and Imaging Agent Delivery Compositions and Methods

A multi-arm, star-shaped polymer composition can be configured for drug delivery and imaging applications in vivo. The star polymer architecture can be synthesized using living radical polymerization techniques, including reversible addition-fragmentation chain transfer and macromolecular design via the interchange of xanthates with a broad range of reaction conditions and functional groups. The star-shaped polymeric carriers can be tailored for preferential delivery of chemotherapeutics into the tumor-draining lymphatics via subcutaneous, peritumoral or intratumoral injections. The carriers can be loaded with the chemotherapeutic agents from about 10% to about 25% w/w. In addition, the carriers can be loaded with imaging agents from about 5% to about 10% w/w. The molecular weights of the polymeric carriers can be about 40 kDa to about 130 kDa. The chemotherapeutics can be cisplatin, geldanamycin or nitric oxide-donating prodrugs. The imaging agent can be a near-infrared dye, such as IR820.

Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound

Here we report a number of novel JS-K structural analogues with sub-micromolar anti-proliferative activities against human leukemia cell lines HL-60 and U937; JS-K is the anti-cancer lead compound O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)pip