90359-82-3Relevant academic research and scientific papers
Directed Metalation of N,N-Diethylbenzamides. Silylated Benzamides for the Synthesis of Naturally Occurring pero-Methylanthraquinones and peri-Methyl Polycyclic Aromatic Hydrocarbons
Mills, Robert J.,Snieckus, Victor
, p. 4386 - 4390 (2007/10/02)
Efficient methodologies based on directed ortho metalation, fluoride-induced carbodesilylation, and metal-halogen exchange processes (Scheme I) are reported for the synthesis of peri-methyl-substituted anthraquinone natural products 5 and polycyclic aroma
SILICON IN BENZAMIDE DIRECTED ORTHO METALATION REACTIONS. CARBO- AND BROMO-DESILYLATIONS AND SYNTHESIS OF NATURALLY-OCCURING ANTHRAQUINONES
Mills, R.J.,Snieckus, V.
, p. 483 - 486 (2007/10/02)
Silylated benzamides 2, avaible by directed ortho metalation, undergo fluorideinduced carbodesilylation and ipso bromodesilylation to give usefully-substituted aromatics 3 and 4; these reactions are utilized in a short and efficient synthesis of erythrola
