Delta-aminolevulinic acid dehydratase (ALAD) is an enzyme that plays a crucial role in the biosynthesis of heme, a vital component of hemoglobin. It catalyzes the condensation of two molecules of delta-aminolevulinic acid (ALA) to form porphobilinogen (PBG), which is a key step in the heme synthesis pathway. ALAD is found in various tissues, including the liver, bone marrow, and kidneys. Deficiency or dysfunction of this enzyme can lead to conditions such as lead poisoning, as lead inhibits ALAD activity, and porphyria, a group of disorders characterized by the accumulation of heme precursors in the body. Understanding the function and regulation of ALAD is essential for diagnosing and managing these conditions.
The CAS Registry Mumber 9036-37-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 6 respectively; the second part has 2 digits, 3 and 7 respectively. Calculate Digit Verification of CAS Registry Number 9036-37: (6*9)+(5*0)+(4*3)+(3*6)+(2*3)+(1*7)=97 97 % 10 = 7 So 9036-37-7 is a valid CAS Registry Number.
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