90367-97-8Relevant academic research and scientific papers
Exotic amino acids. 8. Synthesis of monomethyl esters of N-aryl-aminomethylenemalonic acids
Zicane,Ravina,Tetere,Rijkure,Petrova,Kalejs
, p. 840 - 845 (2007/10/03)
N-Arylaminomethyleneisopropylidenemalonates, obtained from ethoxymethyleneisopropylidenemalonate and aromatic amines, underwent methanolysis to form monomethyl esters of N-arylaminomethylenemalonic acids. The conditions of their formation and their yields depend on the nature and positions of the substituents in the aromatic ring of the initial amine.
Reactive Nitrogenous Molecules from Meldrum's Acid Derivatives, Pyrrole-2,3-diones, and Isoxazolones
Briehl, Horst,Lukosch, Adelheid,Wentrup, Curt
, p. 2772 - 2779 (2007/10/02)
Flash vacuum pyrolysis of 5-(aminomethylidene)-2,2-dimethyl-1,3-dioxane-4,6-diones (Meldrum's acid derivatives) 12 gives 4-hydroxyquinolines/4-quinolones 15 or 3-enaminoacroleins 22 in good to excellent yields.Intermediate (aminomethylene)ketenes and imidoylketenes are directly observed and their transformation into product 22 monitored by low-temperature IR spectroscopy.Imidoylketenes are also formed and observed upon thermal CO extrusion from pyrrole-2,3-diones 16.Isocyanoamines and fulminates are generated by pyrolysis of hydrazono- or oximino-Meldrum's acid derivatives 32 and 39, monitored by IR spectroscopy, and found to rearrange to cyanamides and cyanates, depending on substituents.The thermal reactions of isoxazol-5(4H)-ones and Meldrum's acid derivatives are compared and discussed.
