90381-89-8Relevant academic research and scientific papers
Selective Synthesis of α-Sulphenyl-, α-Sulphinyl-, and α-Sulphonyl-α,β-unsaturated Carbonyl Compounds by the Knoevenagel Reaction
Tanikaga, Rikuhei,Tamura, Tadashi,Nozaki, Yoshihito,Kaji, Aritsune
, p. 87 - 88 (1984)
Simple treatment of aldehydes with the carbonyl compounds (1) 2COCH2S(O)nAr; n = 0, 1, 2> and piperidine stereoselectively produces the condensation products (7), the stereochemistry of which is controlled by the steric requirements of two fu
Enantioselective synthesis of α-hydroxy thioesters via oxazaborolidine- mediated reduction of α-phenylthio enones
Berenguer, Ramon,Cavero, Marta,Garcia, Jordi,Munoz, Montse
, p. 2183 - 2186 (2007/10/03)
α-Phenylthio-α,β-alkenones (2), readily available by Pd(II)-catalysed coupling of (E)-1 phenylthio-1-tributylstannylhex-1-ene with the corresponding acid chlorides have been treated with borane in the presence of phenylglycine- or proline-derived oxazaborolidines to afford 2-phenylthio-2- alken-1-ols (3) with good to excellent enantioselectivities. Ozonolysis of 3 provides a new and efficient route to chiral α-hydroxy thioesters 4.
