903906-55-8

Upstream product

• 77-76-9 2,2-dimethoxy-propane 
• 628308-75-8 (2S,3S,4R,5R,6S)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyranol 

Downstream Products

• 903906-56-9 p-tolyl 2,3-O-isopropylidene-4-O-(4-methoxybenzyl)-1-thio-α-L-rhamnopyranoside 
• 1158796-37-2 (2R,3R,4S,5R)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-6-p-tolylsulfanyl-tetrahydro-pyran 
• 903906-57-0 2-(trimethylsilyl)ethyl 2,3-O-isopropylidene-4-O-(4-methoxybenzyl)-α-L-rhamnopyranosyl-(1->6)-2,3,4-tri-O-acetyl-β-D-galactopyranoside 
• 1053179-21-7 p-tolyl 4-O-benzyl-2,3-O-isopropylidene-1-thio-α-L-rhamnopyranoside 

Relevant academic research and scientific papers

Concise synthesis of a pentasaccharide related to the anti-leishmanial triterpenoid saponin isolated from Maesa balansae

(Chemical Equation Presented) Concise synthesis of the glycone part (a pentasaccharide) of the anti-leishmanial triterpenoid saponin isolated from Maesa balansae is reported. A late-stage TEMPO-mediated oxidation of a primary hydroxyl group to carboxylic

Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategy

Naturally occurring spirostanol saponins bear a chacotriose, α-l-rhamnopyranosyl-(1→2)-[α-l-rhamnopyranosyl-(1→4)] -β-d-glucopyranose residue as the oligosaccharide moiety which is believed to be important for biological activity. Herein the development of a concise, combinatorial method for the synthesis of two series of glycan variants at the 2′ and/or 4′ positions of chacotriose is described and the structure-activity relationships of the glycone part at 3-OH of chlorogenin investigated. These compounds were found to be weakly-cytotoxic toward leukemia cell lines CCRF and HL-20, indicating that the chacotriose moiety is important for anticancer activity.

Convergent synthesis of a trisaccharide as its 2-(trimethylsilyl)ethyl glycoside related to the flavonoid triglycoside from Gymnema sylvestre

The glycone part of the flavonoid triglycoside, kaempferol 3-O-β-d-glucopyranosyl-(1→4)-α-l-rhamnopyranosyl-(1→6)-β-d-galactopyranoside, has been synthesized in good yield and stereoselectivity using N-iodosuccinimide and HClO4-silica promoted