90416-05-0

Basic information

• Product Name: Phenyl-phosphinsaeure-(γ-chlor-propyl)-ester
• Synonyms: Phenyl-phosphinsaeure-(γ-chlor-propyl)-ester
• CAS NO: 90416-05-0
• Molecular Weight: 218.62
• Mol File: 90416-05-0.mol

Chemical Properties

• CAS DataBase Reference: Phenyl-phosphinsaeure-(γ-chlor-propyl)-ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenyl-phosphinsaeure-(γ-chlor-propyl)-ester(90416-05-0)
• EPA Substance Registry System: Phenyl-phosphinsaeure-(γ-chlor-propyl)-ester(90416-05-0)

Safety Data

• Hazardous Substances Data: 90416-05-0(Hazardous Substances Data)

Upstream product

• 1779-48-2 phenylphosphinic acid 
• 628-11-5 3-chloropropyl chloroformate 
• 644-97-3 Dichlorophenylphosphine 
• 7526-32-1 2-phenyl-[1,3,2]dioxaphosphinane 

Relevant articles and documents

Silver(I) Promoted the C4-H Bond Phosphonation of 1-Naphthylamine Derivatives with H-Phosphonates

A simple and efficient protocol for silver-promoted direct C-H phosphonation of 1-naphthylamine derivatives with H-phosphonates was described. This reaction proceeded smoothly for 1-naphthylamine derivatives at the C4 site, providing a facile and efficient route to 4-phosphonated 1-naphthylamine derivatives. This phosphonation could tolerate a diverse type of functional groups at the pyridinyl and naphthyl moieties. Further functionalization of the phosphonated product was also explored at the C2 and C8 sites, such as fluoridation, methylation, methoxylation, and amination. In addition, DFT studies of the reaction intermediate showed that the most electrophilic reactive site is at the C4 site in the naphthyl ring.