904236-90-4Relevant academic research and scientific papers
A metal-free tandem demethylenation/C(sp2)-H cycloamination process of N -Benzyl-2-aminopyridines via C-C and C-N bond cleavage
Liang, Dongdong,He, Yimiao,Liu, Lanying,Zhu, Qiang
, p. 3476 - 3479 (2013)
A mild, metal-free synthesis of pyrido[1,2-a]benzimidazoles starting with N-benzyl-2-aminopyridines, which employs PhI(OPiv)2 as a stoichiometric oxidant, has been developed. The process is initiated by an unusual PhI(OPiv)2-mediated ipso SEAr reaction, followed by solvent-assisted C-C and C-N bond cleavage.
Copper(I)-catalyzed [3+2] cycloaddition/ring-opening rearrangement/[4+2] cycloaddition/aromatization cascade: An unprecedented chemo- and stereoselective three component coupling of sulfonyl azide, alkyne and N-arylidenepyridin-2- amine to pyrido[1,2-a]pyrimidin-4-imine
Namitharan, Kayambu,Pitchumani, Kasi
supporting information, p. 93 - 98 (2013/03/13)
A novel synthetic protocol for the one-pot chemo- and stereoselective construction of diversely functionalized pyrido[1,2-a]pyrimidin-4-imines via copper(I)-catalyzed [3+2] cycloaddition/ring-opening rearrangement/[4+2] cycloaddition/aromatization cascade of sulfonyl azides, alkynes and N-arylidenepyridin-2-amines under mild reaction conditions is reported. In addition, the catalytic activity of copper(I)-modified zeolite, a recyclable, heterogeneous catalyst is also investigated, which gives improved yield compared to its homogeneous equivalents. Copyright
Ultrasonics promoted synthesis of thiazolidinones from 2-aminopyridine and 2-picolilamine
Gouvêa, Daniela P.,Bare?o, Valéria D.O.,Bosenbecker, Juliano,Drawanz, Bruna B.,Neuenfeldt, Patrícia D.,Siqueira, Geonir M.,Cunico, Wilson
experimental part, p. 1127 - 1131 (2012/08/08)
The efficient multicomponent synthesis of thiazolidinones from the reaction of arenealdehydes, mercaptoacetic acid and 2-picolilamine or 2-aminopyridine under ultrasound irradiation are reported. The reaction with 2-aminopyridine needs a Lewis acid cataly
Simple and efficient one-pot synthesis of imidazo[1,2-a]pyridines catalyzed by magnetic nano-Fe3O4-KHSO4·SiO 2
Guntreddi, Tirumaleswararao,Allam, Bharat Kumar,Singh, Krishna Nand
, p. 2635 - 2638,4 (2012/12/12)
The present report highlights a magnetic nano-Fe3O 4-KHSO4·SiO2 catalyzed synthesis of imidazo[1,2-a]pyridines. The synthetic strategy adopted is expedient, versatile, and offers good to excellent yields from readily available starting materials.
