904291-46-9Relevant academic research and scientific papers
Extended Length Borane Phosphonate Nucleic Acid Compounds
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Page/Page column 10, (2010/02/17)
The present invention provides a novel method for solid-phase phosphoramidite based synthesis of borane phosphonate DNA. Also provided are novel phosphoramidite molecules, novel extended length borane phosphonate nucleic acid compounds, and methods of use
Synthesis and biochemical activity of new oligonucleotide analogs
McCuen, Heather Brummel,Noe, Mary S.,Olesiak, Magdalena,Sierzchala, Agnieszka B.,Caruthers, Marvin H.,Higson, Adrian P.
experimental part, p. 349 - 363 (2009/04/07)
Borane phosphonate deoxyoligonucleotides are synthesized from 5′-O-benzhydroxybis(trimethylsilyloxy)silyl-2′-deoxynucleoside- 3′-phosphoramidites. The exocyclic amines of adenine and cytosine are protected with dimethoxytrityl and trimethoxytrityl, respec
