904673-83-2Relevant academic research and scientific papers
Intramolecular oxidative rearrangement: I2/TBHP/DMSO-mediated metal free facile access to quinoxalinone derivatives
Slathia, Nancy,Gupta, Annah,Kapoor, Kamal K.
, (2021/07/25)
Iodine/TBHP/DMSO mediated oxidative rearrangement of 3-styrylquinoxalin-2(1H)-one led to the formation of 3-aroylquinoxalin-2(1H)-ones in good to high yields via Kornblum oxidation. This methodology proceeds under mild conditions via oxidative aryl migrat
Eosin Y as a direct hydrogen-atom transfer photocatalyst for the C3-H acylation of quinoxalin-2(1H)-ones
Ni, Hangcheng,Li, Yu,Shi, Xingzi,Pang, Yi,Jin, Congying,Zhao, Fei
supporting information, (2021/03/03)
Visible light promoted eosin Y catalyzed selective C3-H acylation of quinoxalin-2(1H)-ones has been developed in a green and sustainable manner. In contrast to the conventional anionic eosin Y-based photoredox process, neutral eosin Y acts as the actual c
Metal-free C3-H acylation of quinoxalin-2(1: H)-ones with α-oxo-carboxylic acids
Li, Yu,Ni, Hangcheng,Shi, Xingzi,Zhang, Xiaoning,Zhao, Fei,Zhao, Jingwei
, p. 6558 - 6563 (2020/09/04)
Direct C3-H acylation of quinoxalin-2(1H)-ones with α-oxocarboxylic acids under thermo conditions promoted by PIDA has been achieved in a moderate to good yield in a very fast manner. Mechanistic study revealed that the reaction proceeds via a radical pro
Novel 3-benzoyl-2-piperazinylquinoxaline derivatives as potential antitumor agents
Piras, Sandra,Loriga, Mario,Carta, Antonio,Paglietti, Giuseppe,Costi, M. Paola,Ferrari, Stefania
, p. 541 - 548 (2007/10/03)
A series of new benzoylquinoxaline derivatives (7-26) was synthesized and evaluated for antitumor activity against a panel of 60 human cell lines at the NCI of Bethesda. Among the compounds which have passed the preliminary screening, compound 23 exhibite
